Protein Alignment Mct1 and Sln

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 175/681 - (25%)
• Similarity: 291/681 - (42%)
• Gaps: 145/681 - (21%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTA-WIASIMVGVTFSSGPIS 91
            |||||:||.:|||:|.:.....|:..|:|:.|.|.::.|.......| ||.:|:..:.....|:|
  Fly   225 PPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVLAPLS 289

  Fly    92 SSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEA 156
            |:...|:.||.|...|.|..|..:|:|.||.::|.|::|.|..||:|.||...|.||.|:|||:.
  Fly   290 SALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDK 354

  Fly   157 KRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQT 221
            .|:||.||.|.|:..|:|:...|.:.|..|.|:.|.:||:||.:|:..:...::||:
  Fly   355 HRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPI-------- 411

  Fly   222 PPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKD------------QYLQLPQRTDTA-VSGGA 273
                         ||..||::...:.|..|.|.:|            .||      ||. |..|.
  Fly   412 -------------SAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYL------DTCDVGAGH 457

  Fly   274 LCRSNSVGHNLKPNLNNNSNGAVNGQ------------------GPTLVTPPQAVVKST------ 314
            ......:.|.......|:.|...:.|                  |.|....|...|:|:
  Fly   458 ELSDKFIEHLFLEESKNHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSV 522

  Fly   315 ------------------------------SNDDIARKCHSQLQ--LTPLRDAHRERSASGTMYR 347
                                          :||::..|..:.|:  |:|.....|..|.|
  Fly   523 EDLSTDSTWVYRKHSGTDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKS----- 582

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSR------------SMSGSGVIKRYGSLRQSNNVSQSQEEA-- 398
                     ..:|..||:.:||.:            |.....:|...|.|....:....:|..
  Fly   583 ---------MEIPTPVSNLSDLKQQPVEQAELGILDSQLVESIIDGDGHLAADEDDDDDEERGPR 638

  Fly   399 KCCGCITCSKETRDTFAEM-MNFSLLKDMVFVIFSVSNFCTSIGFNVPYL--YVVAYAETLKLTK 460
            .||..|           || ::.|||:|..|::..:|....|:|  .||:  |:.|:..::...|
  Fly   639 TCCERI-----------EMYLDISLLQDPSFILMCLSVTLMSVG--CPYMLYYLPAHVISIGYNK 690

  Fly   461 TDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCV 525
            ::|.||::...|.:.:||:.||::.|....:|...|.:|:...|.:...:|.......:.....|
  Fly   691 SEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLCILGAGCAVLTIPFAKTLVLVGLSAAV 755

  Fly   526 FGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAG 590
            :|..:|::..|..|:|.|:.|.|::::::||:.:||.|.:...||:.|.|.||:..|...|...|
  Fly   756 YGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMG 820

  Fly   591 --LMIAISGLVMFAIPPLQ--RLQVRKSERK 617
              :::..:.|::::|...:  ||.|::.|.:
  Fly   821 SCMVLGTTPLIVWSILEARNHRLFVQREEEE 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	165/658 (25%)
Sln	NP_610706.1	MFS_MCT_SLC16	231..>409	CDD:340910	65/177 (37%)
		MFS	<652..834	CDD:475125	50/183 (27%)