Protein Alignment Mct1 and hrm

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 184/659 - (27%)
• Similarity: 306/659 - (46%)
• Gaps: 83/659 - (12%)

  Fly     6 PARRKSQQQHEACEM-----DMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDY 65
            |....::.:|:...:     |.|....||||||||:|:.||.:.:|:..|...|||:.::||.|.
  Fly    22 PNGNTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDA 86

  Fly    66 FNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIIT 130
            ||......|||.::...:..|.||:||....:|..|.||:.|...|:..:|:|.:|.::..|.|:
  Fly    87 FNSSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYIS 151

  Fly   131 IGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLI 195
            .|...|:|.||.:.|.:..||.||...|.||.|:.:.||..|:.:..||..:|:..||:.|:.||
  Fly   152 YGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLI 216

  Fly   196 IGGIVLNCIIFGAMFRPLE------------LEAPPQ----------------TPPNTPSTPKLA 232
            :|||.||..:....:.|:|            ||..|:                .|.|.|:...|
  Fly   217 MGGITLNVFVAALFYEPVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPL- 280

  Fly   233 KKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAV------SGGAL-CRSNSVGHNLK-PNLN 289
                 :..|:..:.|    .||.|:.||..:....||      ||... .||..:...:: |..|
  Fly   281 -----LPYNSPPSPL----YLPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRN 336

  Fly   290 NN-SNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRER------SASGTMYR 347
            .. :.|.:|.|. :|...|:.  :|:||           :|| ||::.:.|      |.|..:|.
  Fly   337 QTFTPGQLNSQS-SLYAVPEG--RSSSN-----------KLT-LRNSSKSRLSKRSPSTSSFLYV 386

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
            ....:..:|...|...||...| |||..||.    |....|.....|..:....|  ...:..|.
  Fly   387 STPYHGSTLSFQPKEFSSHLSL-RSMGSSGT----GHAGDSTGQDGSYADVDARG--QAQQPQRS 444

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
            .|.::   |||||.::::..:||...:|.:....:.:.::.|.....|:.::||:|.:...:.:|
  Fly   445 KFFDL---SLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIG 506

  Fly   478 RIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILV 542
            ||....:||..::.:...:...|:..|:|.|::|....:.|:.|:|.:||...|.|||:|:||:.
  Fly   507 RIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMA 571

  Fly   543 DLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQ 607
            |:||.::||:::|:.|...|:...:|||:..:.::..:.|.|.|...||.:.....:...:|.:.
  Fly   572 DMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFMPWIN 636

  Fly   608 RLQVRKSER 616
            |.:....|:
  Fly   637 RRKANAEEQ 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	63/177 (36%)
		MFS	<426..604	CDD:119392	46/177 (26%)
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	180/632 (28%)
		MFS	59..>234	CDD:119392	61/174 (35%)
		MFS	<449..633	CDD:119392	51/186 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I4618
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I274
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
	9	8.970