Protein Alignment Mct1 and slc16a3b

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_997873.1
• Gene: slc16a3b / 327276
• ZFINID: ZDB-GENE-030131-5487
• Length: 508
• Species: Danio rerio
• Alignment Length: 596
• Identity: 145/596 - (24%)
• Similarity: 240/596 - (40%)
• Gaps: 195/596 - (32%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGP 89
            |||||||.|:||.|:|    .|.:|:|    .:|:.|.:..|..|...||||:||::.:.:.:||
Zfish    16 PDGGWGWAVLFGCFII----TGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGP 76

  Fly    90 ISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYF 154
            :.|..|||:|||.|.:.|.:.|:..::::.||.|::.:.:..|..||||..|.:.|:::.:.:||
Zfish    77 LCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYF 141

  Fly   155 EAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPP 219
            ..||.||.|:|..||.......:||.:.|...|||||..||:||::|||...||:.|||
Zfish   142 SEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPL------ 200

  Fly   220 QTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNL 284
                       ||.|      .|:..|.:|.:..||
Zfish   201 -----------LAPK------KTSEVEEKPKETKPK----------------------------- 219

  Fly   285 KPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPD 349
                                                                             
Zfish   220 ----------------------------------------------------------------- 219

  Fly   350 ALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTF 414
                                                                             
Zfish   220 ----------------------------------------------------------------- 219

  Fly   415 AEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRI 479
            .::::|::.||..|:|::::.....:|..||.::||:||:.|....|.::.|::.:|..:...|.
Zfish   220 PKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARP 284

  Fly   480 ILGYISDKPWVNRLLVY--NVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILV 542
            ..|.|:...||....||  :..:...|::..:.....|:.||..:|..||.:.|....|...:|:
Zfish   285 TSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLM 349

  Fly   543 DLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQ 607
            .::|.:|.::|.||:||.:.||..:|||..|.:.|.|.:|...|::||..:.:|.||: ||..|
Zfish   350 AIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYVFMLAGCEVVLSALVL-AICNL- 412

  Fly   608 RLQVRKSERKP 618
             |.:::..::|
Zfish   413 -LFIKRKPQQP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	69/181 (38%)
		MFS	<426..604	CDD:119392	53/179 (30%)
slc16a3b	NP_997873.1	MFS	22..410	CDD:119392	135/574 (24%)
		MFS_1	25..376	CDD:284993	119/536 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578912
Domainoid	1	1.000	142	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.750