Protein Alignment Mct1 and Slc16a11

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_038941393.1
• Gene: Slc16a11 / 287450
• RGDID: 1311125
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 120/584 - (20%)
• Similarity: 219/584 - (37%)
• Gaps: 195/584 - (33%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISS 92
            ||||||||||...:|.::.::.|:..|.|:...:..::|......|||::::.:.|..::.|:.|
  Rat   154 PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGS 218

  Fly    93 SFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAK 157
            :...|:|.|.|.:.|.:|.:..::.|.||:::|.|.:.:|...|.|:.|::.||:.::::||..:
  Rat   219 ALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRR 283

  Fly   158 RSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTP 222
            |.||.|:|:.|:|..:.:.||..:||:..:|||||:|::|.:.|:....||:.|||.|...|..|
  Rat   284 RVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAP 348

  Fly   223 PNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPN 287
            |.||
  Rat   349 PRTP------------------------------------------------------------- 352

  Fly   288 LNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALY 352
                                                     |..|
  Rat   353 -----------------------------------------LAAL-------------------- 356

  Fly   353 QGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEM 417
                                  |.|:.:|
  Rat   357 ----------------------GLGLFRR------------------------------------ 363

  Fly   418 MNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILG 482
                    ..|.:|::.......|:.|||:::..:|....:....|:.:::...|.:...|::.|
  Rat   364 --------PAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDASARLVSG 420

  Fly   483 YISDKPWV--NRLLVYNVCLTACGV-STAMVPLCHDFQS----LAFYCCVFGFTIGAYVGLTSVI 540
            :::|:.||  .||||....||..|| :..:||.....:.    |......:|.:.|:|..|...:
  Rat   421 WLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGV 485

  Fly   541 LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIP 604
            |..|:|:..:..|.||:::...:...:|||:.|::.|.|..::.:||:....|.....:...:|
  Rat   486 LPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	55/177 (31%)
		MFS	<426..604	CDD:119392	44/184 (24%)
Slc16a11	XP_038941393.1	PHA03378	<42..158	CDD:223065	3/3 (100%)
		MFS_MCT11_13	160..549	CDD:340981	113/576 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339250
Domainoid	1	1.000	147	1.000	Domainoid score	I4382
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850