Protein Alignment Mct1 and Slc16a1

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_036848.1
• Gene: Slc16a1 / 25027
• RGDID: 3690
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 141/608 - (23%)
• Similarity: 230/608 - (37%)
• Gaps: 181/608 - (29%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||||||||.||.|:|    ::.|.:|:|    .:|:.|....|:......:||:|||:.|.::.
  Rat    12 TPPDGGWGWAVVVGAF----ISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            |||||..||:||.|.|.|||..|:...:|.:.|...|..|...||...|||......||:..:.:
  Rat    73 GPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..||.||.|:|:.||.......|||.:...|.:||||:.||:||::|||.:.|::.||:
  Rat   138 YFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPI---- 198

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
                .|......||..|.::
  Rat   199 ----GPQQGKVEKLKSKESL--------------------------------------------- 214

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                                     |...||.:|.|:
  Rat   215 -------------------------QEAGKSDANTDL---------------------------- 226

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
                                              .|...:...:|..|
  Rat   227 ----------------------------------IGGSPKGEKLSVFQ----------------- 240

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
            |..:.::.||.....|:::...|.....|...|.:::..|.::...:...:::|:|.:...:.|.
  Rat   241 TVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVA 305

  Fly   478 RIILGYISDKPWVNRLLVY--NVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI 540
            |..:|..::..|:...:.|  ...:.|.||...:.||...:.....|..||||..|   .|:||:
  Rat   306 RPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFG---WLSSVL 367

  Fly   541 ---LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMF- 601
               |:||:|..:.::|.||:.:.:.....:|||:.|.:.|:...|...:...|:::.|:||.:|
  Rat   368 FETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFI 432

  Fly   602 -------AIPPLQRLQVRKSERK 617
                   .:...|:.:.:|.:.|
  Rat   433 GMGINYRLVAKEQKAEEKKRDGK 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	70/181 (39%)
		MFS	<426..604	CDD:119392	44/190 (23%)
Slc16a1	NP_036848.1	2A0113	1..462	CDD:273325	141/608 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..494		2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm12325
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.850