Protein Alignment Mct1 and Slc16a4

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_666248.1
• Gene: Slc16a4 / 229699
• MGIID: 2385183
• Length: 500
• Species: Mus musculus
• Alignment Length: 598
• Identity: 164/598 - (27%)
• Similarity: 271/598 - (45%)
• Gaps: 114/598 - (19%)

  Fly    23 ERQPTP---P-DGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGV 83
            |:.|:|   | ||||||:||...|::::...|||.:|.||:..|.:.|........||.|||..:
Mouse     5 EKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSL 69

  Fly    84 TFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIV 148
            .||:||:::...:..|.:|.:|.|:.|.:...::|.:|..:..|.:|:|...|||...:|..|.|
Mouse    70 RFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAV 134

  Fly   149 SVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPL 213
            .:|:||:.:..|:|.||..|.|. ||:.||.|:|||..|.|.||:::.|.|:||.:....:.||:
Mouse   135 VITKYFKKRLGLSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPI 198

  Fly   214 ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSN 278
            ..::
Mouse   199 HSQS------------------------------------------------------------- 202

  Fly   279 SVGHNLKPNLNNNSNGAVNGQGPTL-VTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSAS 342
                      ||||:  :..:|..| .|.|:|..|:.::     || .:.|...::|:..::|..
Mouse   203 ----------NNNSD--IENKGSILSATEPEASYKTETS-----KC-KETQEPFIKDSTMKKSEQ 249

  Fly   343 GTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCS 407
            .|....      .|.|..:..|:|...:|            .|..||..|..::....    .|.
Mouse   250 PTTTLT------VLGNQSEEFSNRPHRNR------------PLLMSNGKSHKKKFVSW----NCK 292

  Fly   408 KETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGV 472
            :       ::::.||.::..|.||:.|...:.:.:.:|..::||.|:||.:...|||||:|..|:
Mouse   293 Q-------KLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGI 350

  Fly   473 ANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLT 537
            ..||.::|.|:|:|:.|:.:...:...|..|||:..:.||...|..|..|..:|....|.|:.|.
Mouse   351 TETVSQLISGWIADQNWIKKYQYHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALI 415

  Fly   538 SVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFA 602
            ..:||||....::....|....|.|||...||||.||:||.|.:|..:|..:|....:|.:.:|.
Mouse   416 LPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFF 480

  Fly   603 IPPLQRLQVRKSE 615
            :|..:|.:.::|:
Mouse   481 VPLAERWKRKQSD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	63/177 (36%)
		MFS	<426..604	CDD:119392	60/177 (34%)
Slc16a4	NP_666248.1	2A0113	7..479	CDD:273325	159/580 (27%)
		MFS	24..482	CDD:119392	150/566 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm11108
orthoMCL	1	0.900	-	-		OOG6_109218
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.750