Protein Alignment Mct1 and Slc16a4

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_666248.1
• Gene: Slc16a4 / 229699
• MGIID: 2385183
• Length: 500
• Species: Mus musculus
• Alignment Length: 598
• Identity: 164/598 - (27%)
• Similarity: 271/598 - (45%)
• Gaps: 114/598 - (19%)

  Fly    23 ERQPTP---P-DGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGV 83
            |:.|:|   | ||||||:||...|::::...|||.:|.||:..|.:.|........||.|||..:
Mouse     5 EKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSL 69

  Fly    84 TFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIV 148
            .||:||:::...:..|.:|.:|.|:.|.:...::|.:|..:..|.:|:|...|||...:|..|.|
Mouse    70 RFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAV 134

  Fly   149 SVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPL 213
            .:|:||:.:..|:|.||..|.|. ||:.||.|:|||..|.|.||:::.|.|:||.:....:.||:
Mouse   135 VITKYFKKRLGLSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPI 198

  Fly   214 ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSN 278
            ..::
Mouse   199 HSQS------------------------------------------------------------- 202

  Fly   279 SVGHNLKPNLNNNSNGAVNGQGPTL-VTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSAS 342
                      ||||:  :..:|..| .|.|:|..|:.::     || .:.|...::|:..::|..
Mouse   203 ----------NNNSD--IENKGSILSATEPEASYKTETS-----KC-KETQEPFIKDSTMKKSEQ 249

  Fly   343 GTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCS 407
            .|....      .|.|..:..|:|...:|            .|..||..|..::....    .|.
Mouse   250 PTTTLT------VLGNQSEEFSNRPHRNR------------PLLMSNGKSHKKKFVSW----NCK 292

  Fly   408 KETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGV 472
            :       ::::.||.::..|.||:.|...:.:.:.:|..::||.|:||.:...|||||:|..|:
Mouse   293 Q-------KLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGI 350

  Fly   473 ANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLT 537
            ..||.::|.|:|:|:.|:.:...:...|..|||:..:.||...|..|..|..:|....|.|:.|.
Mouse   351 TETVSQLISGWIADQNWIKKYQYHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALI 415

  Fly   538 SVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFA 602
            ..:||||....::....|....|.|||...||||.||:||.|.:|..:|..:|....:|.:.:|.
Mouse   416 LPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFF 480

  Fly   603 IPPLQRLQVRKSE 615
            :|..:|.:.::|:
Mouse   481 VPLAERWKRKQSD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	153/570 (27%)
Slc16a4	NP_666248.1	MFS_MCT5	20..486	CDD:340979	154/574 (27%)