Protein Alignment Mct1 and SLC16A9

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 166/637 - (26%)
• Similarity: 266/637 - (41%)
• Gaps: 163/637 - (25%)

  Fly    20 MDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVT 84
            |::::.   ||||||||:||.||:...:..|...:.|:.|.|:||.|.||||.|||:.|:..||.
Human     1 MELKKS---PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVG 62

  Fly    85 FSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVS 149
            ..:.|:.|..|:.:|.|.|||....:.|..:::|.||.|:..|..:.|...|||.||:|...:..
Human    63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTI 127

  Fly   150 VTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLE 214
            ..|||:.:|.||.|:...||..|.|::|.|...|:..||..|.:||:|.:.||.:..|::.|||:
Human   128 TCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQ 192

  Fly   215 LEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNS 279
            ....|.                            |.|:.|:|    ||.:...         .|.
Human   193 SSDCPL----------------------------PKKIAPED----LPDKYSI---------YNE 216

  Fly   280 VGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGT 344
            .|.||:.|:|                   .:.||.|:::   ||...|             |:|.
Human   217 KGKNLEENIN-------------------ILDKSYSSEE---KCRITL-------------ANGD 246

  Fly   345 MYRPDALYQGSLHNLPDYVSSRND-------LSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCG 402
             ::.|:|    ||..|....::..       ..::.....:.||...|.::           .||
Human   247 -WKQDSL----LHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKN-----------YCG 295

  Fly   403 CITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTD-ASYL 466
                  ||         .:|.|:.||....::.....||...|.|.:...|.:..:.:.: ...|
Human   296 ------ET---------VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPL 345

  Fly   467 ISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIG 531
            ||.||:...||:::||.::|..|:|.|.:|...|...|::...:|....:.:||....:.||..|
Human   346 ISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTG 410

  Fly   532 AYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPI------------------------- 571
            .: .:...:....:|::||.:|:|:|:.|.|:.:.:||||
Human   411 NW-SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGKIFILKSSHFTVLPCHISRYRGP 474

  Fly   572 -----------------GGWMYDLTDSYAPAFLMAGLMIAISG--LVMFAIP 604
                             .||.||.|.:|..||..:|..:.:.|  |::.|:|
Human   475 DCNSSTDLYKRNLHGTSHGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAALP 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	159/621 (26%)
SLC16A9	XP_016871372.1	MFS_MCT9	12..524	CDD:340986	158/619 (26%)