Protein Alignment Mct1 and Slc16a11

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_694721.2
• Gene: Slc16a11 / 216867
• MGIID: 2663709
• Length: 447
• Species: Mus musculus
• Alignment Length: 584
• Identity: 121/584 - (20%)
• Similarity: 218/584 - (37%)
• Gaps: 195/584 - (33%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISS 92
            ||||||||||...:|.::.::.|:..|.|:...:..::|......|||::::.:.|..::.|:.|
Mouse     8 PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGS 72

  Fly    93 SFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAK 157
            :...|:|.|.|.:.|.:|.:..::.|.||:::|.|.:.:|...|.|:.|::.||:.::::||..:
Mouse    73 ALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRR 137

  Fly   158 RSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTP 222
            |.||.|:|:.|:|..:.:.||..:||:..:|||||:|::|.:.|:....||:.|||.|...|..|
Mouse   138 RVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAP 202

  Fly   223 PNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPN 287
            |.||
Mouse   203 PRTP------------------------------------------------------------- 206

  Fly   288 LNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALY 352
                                                     |..|
Mouse   207 -----------------------------------------LAAL-------------------- 210

  Fly   353 QGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEM 417
                                  |.|:.||
Mouse   211 ----------------------GLGLFKR------------------------------------ 217

  Fly   418 MNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILG 482
                    ..|.:|::.......|:.|||:::..:|....:....|:.:::...|.:...|:..|
Mouse   218 --------RAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASG 274

  Fly   483 YISDKPWV--NRLLVYNVCLTACGV-STAMVPLCHDFQS----LAFYCCVFGFTIGAYVGLTSVI 540
            :::|:.||  .||||....||..|| :..:||.....:.    |......:|.:.|:|..|...:
Mouse   275 WLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGV 339

  Fly   541 LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIP 604
            |..|:|:..:..|.||:::...:...:|||:.|::.|.|..::.:||:....|.....:...:|
Mouse   340 LPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLP 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	55/177 (31%)
		MFS	<426..604	CDD:119392	44/184 (24%)
Slc16a11	NP_694721.2	MFS	14..403	CDD:391944	114/576 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950