Protein Alignment Mct1 and mct-1

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_503655.2
• Gene: mct-1 / 189489
• WormBaseID: WBGene00021227
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 182/614 - (29%)
• Similarity: 278/614 - (45%)
• Gaps: 124/614 - (20%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSFG-IFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPI 90
            ||||||:|||||..||::::..||:.|:.| |....:.|.|. .......:.||:.|..:.:||:
 Worm    38 TPPDGGYGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQFG-STSVAGAVISILTGCYYLAGPL 101

  Fly    91 SSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFE 155
            :|||||.:|.|:|.|||||||.:..::|.||..:..|.:..|...|:|||.:|||:||.::.||.
 Worm   102 ASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVLGGIGFGCMYLPSIVILSTYFA 166

  Fly   156 AKRSLATGIAVCGSGFGTFVFA----PLTEFL---IGNYGWRGAMLIIGGIVLNCIIFGAMFRPL 213
            .|||:||||||||||.||.||:    |:.::.   :|::     |:.:..|.::..:|..:|.||
 Worm   167 KKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVGSF-----MVYLAAIAISGSLFSLLFAPL 226

  Fly   214 ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSN 278
            :            :|....||.|.:.:|......||.:.|.:|      .|.|       |...|
 Worm   227 K------------ATEHQVKKVAKMVRNYEGKPEEPTQRLLED------VRND-------LEELN 266

  Fly   279 SVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASG 343
            ..|||
 Worm   267 RPGHN------------------------------------------------------------ 271

  Fly   344 TMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSK 408
                .|..|.|   |.|...|..|.|.|..:.|.          ..:|..:.|.......:..||
 Worm   272 ----ADTFYAG---NAPVSRSRSNTLDRKAAESA----------EAHVVHATEHHTVHHVVKKSK 319

  Fly   409 ETRDTFAEMMNFSLLKDMV----FVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDA--SYLI 467
            .|:  |.|.:...|.||::    |:..:||...|.:.|.||::|:....:......|||  |..:
 Worm   320 FTK--FKESLCSVLDKDLLFSPSFMTLAVSGTFTVLSFLVPFVYLALAMKQKNPDFTDAELSLPV 382

  Fly   468 STIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGA 532
            :.||..|.:.||..|.::|.|.::.|.|.||.....|.|...||.|.:......:|..|...:..
 Worm   383 TLIGAFNIMFRIGCGMVADHPKMSALQVSNVATIIAGTSMLFVPFCTELWHYVVFCIPFSAGVAC 447

  Fly   533 YVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISG 597
            :..|.|||.|:|:|::||:||||:|::|.||.:.:|.||...:.|:|.:|..:|.:.|::.|.||
 Worm   448 FAALRSVICVELIGVEKLSNAFGILMVFMGIGAVVGGPIAAQIKDITGNYDISFYVMGIIFAFSG 512

  Fly   598 LVMFAIPPLQRLQVRKSERKPHTEHLALS 626
            ::...:|.|:..:..|...:..||...:|
 Worm   513 VMTIRLPELKAWEESKKLARAGTEMRVIS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	72/185 (39%)
		MFS	<426..604	CDD:119392	59/183 (32%)
mct-1	NP_503655.2	MFS_MCT_SLC16	45..519	CDD:340910	170/583 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820