Protein Alignment Mct1 and mct-3

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_510308.1
• Gene: mct-3 / 181497
• WormBaseID: WBGene00010834
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 191/650 - (29%)
• Similarity: 304/650 - (46%)
• Gaps: 133/650 - (20%)

  Fly    11 SQQQHEACEMDMERQP--TPPDGGWGWVVVFGSFMIHIVTDGMTYSFG-IFYNEFLDYFNEGKGY 72
            :.|..|..|.::|...  .|||||:||.:|..||:::::.||:.::.| |....::..|...:..
 Worm    14 AHQDPETVEKELEDAGFIAPPDGGYGWAIVAASFLLNMIVDGVIFTVGKILQPAWVHSFGISEAS 78

  Fly    73 TAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGL 137
            .|...||:.|..|.:|||:|...|.:|||.|.:|||::||...::|:.|.|:..|.::.|...|.
 Worm    79 AAMTMSILSGCYFFAGPIASVLCNVFGCRQVALAGSLIAALGFLLSISAPNIYVLYVSFGLIAGA 143

  Fly   138 GFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLT----EFLIGNYGWRGAMLIIGG 198
            |||::||||||.::|||..|||:||||||||||.||.|||.|.    :|:.|:  |:..::....
 Worm   144 GFGMMYLPAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVGGD--WKQFLVYTAA 206

  Fly   199 IVLN----CIIFGAMFRPLE------------LEAPPQTPPNTPSTPKLAKKSAIIDQNT----- 242
            :.::    ||    :.|||:            ||...:.....|.:|.|:|      .||
 Worm   207 VTISGLGACI----LLRPLKPSKDQIEKVAKVLEDYEEHKEKVPESPLLSK------HNTPFLSS 261

  Fly   243 ----TAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTL 303
                ||.:||                                            ||...|...::
 Worm   262 LELHTAGKLE--------------------------------------------NGHHTGSIKSI 282

  Fly   304 VTPPQAVVKSTS--NDDIARK----CHSQLQLTPLRDAHRERSASGTMYRPDAL-YQGSLH---- 357
            |   .||.|...  |..:.||    ..|...:.       .||.:|||.|.:|. :|.||.
 Worm   283 V---DAVSKEIEDLNKPLLRKDIFYSGSTTNIA-------ARSRTGTMTREEAAEHQQSLRFRGK 337

  Fly   358 -NLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFS 421
             ..|....|:.||:...:|...|.         |.|:.|             |.:....::::..
 Worm   338 VETPQQYLSKADLNAGDNGDVAIA---------NESKIQ-------------EIKQALKQLVDKE 380

  Fly   422 LLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLK-LTKTDASYLISTIGVANTVGRIILGYIS 485
            ||....|::.:.|...|...|.||::|:..:.:.:: ||..:.|:.:|.|||.|.|.||..|.::
 Worm   381 LLFSPSFLLLAFSGTLTLCCFYVPFIYLGNHLDKIEGLTTAEKSFTVSLIGVLNIVARIGCGILA 445

  Fly   486 DKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKL 550
            |:|.|:.|.|.|..|.|.|::|..|||...:.....:|..|...:..:..|.|:|:|:|:||:||
 Worm   446 DRPEVSALAVNNFALIAAGLATMTVPLYTAYWQFLAFCVPFSIGVACFAALRSIIVVELIGLEKL 510

  Fly   551 TNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSE 615
            :||||:||.|.|:.:.:|.|:...|.|.|.::..:|.:.|.::.|||.:...:..|::.::.:|:
 Worm   511 SNAFGILLTFMGVGAVVGSPLAAAMKDYTGNFDTSFYVMGALMTISGAMCIPLGGLRKRELARSD 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	71/186 (38%)
		MFS	<426..604	CDD:119392	61/178 (34%)
mct-3	NP_510308.1	MFS_MCT_SLC16	39..563	CDD:340910	180/611 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28635
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830