Protein Alignment Mct1 and gem-1

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001379120.1
• Gene: gem-1 / 181458
• WormBaseID: WBGene00008214
• Length: 771
• Species: Caenorhabditis elegans
• Alignment Length: 733
• Identity: 164/733 - (22%)
• Similarity: 282/733 - (38%)
• Gaps: 188/733 - (25%)

  Fly     5 PPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEG 69
            |.:.|......|:.|...|| |...|||:||:||..||::|.|.||.::.|||.:.:..::|..|
 Worm    44 PVSARSDDSDAESVESLTER-PVYKDGGYGWLVVLASFLMHAVCDGASFCFGIVFVKIQEHFQCG 107

  Fly    70 KGYTAWIASIMVGVTFSSGPISSSFVNRYGCR-AVTIAGSILAASCIIVSMFAQNVLTLIITIGF 133
            :..:...||:.:.:.....|::....:..||| ::.|..||...|||| :||..::...:|:.|.
 Worm   108 RFVSMITASMFLSLPLIMSPVAGIVSDILGCRMSIIIGASICTVSCII-AMFCSHIFFFMISFGL 171

  Fly   134 GTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGG 198
            |.|:|...||..|||.||.|||.:|.|||..||.|:|.||.::..|...         :|:.:..
 Worm   172 GCGVGMSFIYNAAIVIVTYYFEKRRGLATSFAVSGTGVGTVIYPILLNL---------SMIYLAS 227

  Fly   199 IV----LNCIIFGAMF----------RPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEP 249
            .|    :..|.|..|:          :.:|.|:.............:||.....:.||.
 Worm   228 FVSDIRIILIFFAVMYFVIAVIGFFIKDVEWESDKTDFKLRKFQKYIAKMDDEKENNTN------ 286

  Fly   250 LKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLN--NNSNGAV-----------NGQGP 301
                |.|.:::      .|:|              .||||  ||.:|::           ....|
 Worm   287 ----PTDAFMR------HAIS--------------LPNLNILNNHSGSIQSICDAAKAERKSDKP 327

  Fly   302 T-------------LVTPPQAVVKSTSNDDIARKCHSQLQL-----TPLRDAHRERSASGTMYRP 348
            |             :.:.|:   .|..|.::|...|..|:|     |.:| |.|.|..|......
 Worm   328 TRSKSVALFDNKHQMSSIPE---YSMLNTNLANLEHLDLELANSPCTTVR-AQRRRVISKVSMSV 388

  Fly   349 DA------------LYQGSLHNLPDYVSSRND--------------------------------- 368
            |.            |:|.|..:..|..||.:|
 Worm   389 DQINELEDEAFHINLFQSSTESESDDESSSDDSEMSNDGDSSSSELSEKNLDEPTTKLINKNLEN 453

  Fly   369 --------------LSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCG--------CITCSKETR 411
                          ::|:...:|....:|....::|..||:.......        .:...|..:
 Worm   454 VAFRATSSVPNSARMNRNSVAAGTSNMFGGRVIASNAIQSRHATNLIAMGKIPSAPMLVARKNRK 518

  Fly   412 DTFAE-MMNF-------------SLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYA-ETLKLTKT 461
            ....: :..|             .::....::..::|..|.....:|||:....|: :|||:.::
 Worm   519 SMIGKPIQGFYKKWLETEKPIYQEVIHCRAYIYLALSVLCLYFILDVPYVCFYEYSIDTLKMEES 583

  Fly   462 DASYLISTIGVANTVGRIILGYISDKPWVNRLL--VYNVCLTACGVSTAMVPLCHDFQSLAFYCC 524
            :|:|:..:||::|.:..::.|.::|  |..:.:  :|...:...|::.......:....|.....
 Worm   584 EANYIYYSIGISNFISVLLFGTLAD--WTRKHITTIYASSMVGVGITIMFSTRINSLVELVIVGV 646

  Fly   525 VFGFTIGAYVGLTSVIL------VDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYA 583
            .||.||.:...|.|:::      |:|..:     |:.|:.:.:|:||.|||||...:.:.|..|.
 Worm   647 CFGVTITSNYVLQSILVTICFEDVNLFQV-----AYSLIAMIEGVASLIGPPIFALVREATGGYT 706

  Fly   584 PAFLMAGLMIAISGLVMF 601
            ..|.::|:....||...|
 Worm   707 VVFFISGIFALASGFFGF 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	60/192 (31%)
		MFS	<426..604	CDD:119392	45/185 (24%)
gem-1	NP_001379120.1	MFS	72..>254	CDD:421695	61/191 (32%)
		MFS	<543..727	CDD:421695	45/189 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920