Protein Alignment Mct1 and mct-4

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 731
• Identity: 211/731 - (28%)
• Similarity: 343/731 - (46%)
• Gaps: 135/731 - (18%)

  Fly     1 MVHGPPARRKSQQQHEACEMDMERQ---------------------------------------- 25
            |..||...|.||.......:..||.
 Worm     1 MTDGPDPNRSSQPTSPTKSLKSERNGESNFEEDDQDIGSLNDGQLTNYSSQYSINMGVQQVEPLL 65

  Fly    26 -PTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGP 89
             |..||||:|||:||.:||.::|.||::.:|..|...:.:.:.|..|.|.:|.|:::|.....||
 Worm    66 VPQAPDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQESDGLTVFIGSLIIGTYLLVGP 130

  Fly    90 ISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYF 154
            :.|:..|:|..|.|.:||.:::....:::..:.|:...::..|...|||||:|||||||.|..||
 Worm   131 LVSALCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIVVVGFYF 195

  Fly   155 EAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPP 219
            ::||::||||:|.|||.|||:...:.:..|.|.||:..:.::..::.:|:.:|.::|||     |
 Worm   196 DSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPL-----P 255

  Fly   220 QTPPNTPSTPKLAKKSAIIDQNTTAAELEPLK-VLPK-----DQYLQL--PQRTDTAVSGGALCR 276
            ....|           .|.||     |:|||: .|.|     |:.::.  |.|:.:|.||.  ..
 Worm   256 MVDLN-----------EIRDQ-----EMEPLRQALSKVEDDEDEAVESPHPNRSTSAASGA--IE 302

  Fly   277 SNSVGHN-----LKPNLNNNSNGAVNGQGPTLVTPPQAVVKS-----TSND------DIAR---K 322
            ..:|..|     |:..|.....|:...:............:|     |||.      .::|   .
 Worm   303 DEAVSQNPEVQRLRSILTEGDEGSETPKSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLS 367

  Fly   323 CHSQLQLTPLRDAHR---ERSASG-------------------TMYRPDALYQGSLHNLPD---- 361
            ..::|.....||.::   :.|.||                   .|.|.|..|.||:.||.:
 Worm   368 SDNRLSRVSARDFNQSLSKLSKSGGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEE 432

  Fly   362 -----YVSSRNDLSRSMSGSGV----IKRYGSLRQSNNVSQSQEEA-------KCCGCITCSKET 410
                 |.:|...:.||:.|..|    :.|.||......:::.:||.       .||..:..  ..
 Worm   433 GTMAGYRASTLSIPRSVVGQAVSQLNLSRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPL--PM 495

  Fly   411 RDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANT 475
            |:..:||::.:|||:...:|..:||....:||.:|.:::...:|::||..:.|.:|:...||.||
 Worm   496 RNALSEMIDLNLLKNKTMMILCISNLLGMMGFYIPIMFLKDLSESMKLDMSLAMFLVPIFGVFNT 560

  Fly   476 VGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI 540
            :||:..|:::|:..::.|.:.|:.|...|:.|...||........||..||||.|.||:.|||::
 Worm   561 IGRVFFGWLTDQKILSALTINNLSLIVSGLLTLACPLLTSIAGQYFYAIVFGFIISAYICLTSIV 625

  Fly   541 LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPP 605
            |.||:||:.|||:||||::.:||||.:|||..|.:||:|.||..||...||::.::||:...||.
 Worm   626 LADLMGLENLTNSFGLLVVARGIASLVGPPFAGIVYDITGSYDTAFYFGGLVLLVAGLISATIPF 690

  Fly   606 LQRLQVRKSERKPHTE 621
            :.:.....::..|..:
 Worm   691 VTKKDADTADGMPQLQ 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	63/177 (36%)
		MFS	<426..604	CDD:119392	69/177 (39%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	63/176 (36%)
		MFS_MCT_SLC16	<507..689	CDD:340910	72/181 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28635
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030