Protein Alignment Mct1 and Slc16a6

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001025013.1
• Gene: Slc16a6 / 104681
• MGIID: 2144585
• Length: 607
• Species: Mus musculus
• Alignment Length: 626
• Identity: 153/626 - (24%)
• Similarity: 271/626 - (43%)
• Gaps: 150/626 - (23%)

  Fly     1 MVHGPPAR---------RKSQQQHEAC-EMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSF 55
            ||.|.|.|         |.:|:..:.| ..::..|  .|||||||.|....|.:.:.|.|:..||
Mouse    67 MVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQ--VPDGGWGWAVAVSFFFVEVFTYGIIKSF 129

  Fly    56 GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMF 120
            |:|:|:.:|.|:|.....:||.||.|.|...:.|:|:...||:|.|.|.:||.:|.:..:|.:.|
Mouse   130 GVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASF 194

  Fly   121 AQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIG 185
            :|.|..:.|:||..:|||:...:||.:..::|||:.:||:.|.:|..|..|..|.|||....|..
Mouse   195 SQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKE 259

  Fly   186 NYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPL 250
            :.|||.::|.:|.:.||.::.||:.||:.::.|.|:|                    .|..|||.
Mouse   260 HIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSP--------------------KAVTLEPR 304

  Fly   251 KVLPKDQYLQLPQRTDTAV----SGGALCRS-NSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAV 310
            :.:   ||:...::|.|::    ||..|..| .:|....|......:.     |..||||.|:
Mouse   305 REV---QYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAE-----QQQTLVTAPK-- 359

  Fly   311 VKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSG 375
                         |||::
Mouse   360 -------------HSQMK----------------------------------------------- 364

  Fly   376 SGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSI 440
                                                   |.:::||:||:..|:.:::.....::
Mouse   365 ---------------------------------------APLLDFSVLKEKSFICYALFGLFATL 390

  Fly   441 GFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGV 505
            ||..|.||::....:|.:....|::|:||:.:|...|||..|::.::..:.::.:..:|:.....
Mouse   391 GFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTA 455

  Fly   506 STAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILV---DLLGLDKLTNAFGLLLLFQGIASFI 567
            |........:|..|......||..:|. :|.|.:.::   |::|::|:::|.|:.:..|.|:...
Mouse   456 SLFAFTFATEFWGLMLCSVFFGSMVGT-IGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLA 519

  Fly   568 GPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQR 608
            |||:.|.:.|.:..|:.||......:.::.:.:..:.|.::
Mouse   520 GPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKK 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	65/177 (37%)
		MFS	<426..604	CDD:119392	40/180 (22%)
Slc16a6	NP_001025013.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..84		5/16 (31%)
		2A0113	101..592	CDD:273325	145/592 (24%)
		MFS	109..556	CDD:119392	137/576 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8713
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850