Protein Alignment Mct1 and slc16a1a

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001243569.1
• Gene: slc16a1a / 100534752
• ZFINID: ZDB-GENE-110408-16
• Length: 461
• Species: Danio rerio
• Alignment Length: 616
• Identity: 140/616 - (22%)
• Similarity: 229/616 - (37%)
• Gaps: 209/616 - (33%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||:|||||.||.|:|    ::.|.:|:|    .:|:.|....||......:||:|||:.|.:..
Zfish    12 TPPEGGWGWAVVLGAF----ISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            ||:||..||:||.|.:.|.|..|:.:.:|.:.|...|..|...:|...|||......||:..:.:
Zfish    73 GPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..||.:|.|||:.||.......|||..:....:||||:.||:||::|||.:.|::.||:
Zfish   138 YFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPI---- 198

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
                                                                             
Zfish   199 ----------------------------------------------------------------- 198

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                             ||    .||..||:
Zfish   199 -----------------GP----KPQPAVKA---------------------------------- 208

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
                                                    .|:.|:::|              |.
Zfish   209 ----------------------------------------DNSNSRAKE--------------RK 219

  Fly   413 TFAEMMN----FSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVA 473
            |..|::|    .:|.|...|:::.:.|.....|...|.:::..||::.::.:..|::|:|.:...
Zfish   220 TVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFV 284

  Fly   474 NTVGRIILGYISDKPW----VNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYV 534
            :.|.|..:|.:::..|    |......::.|.  ||...:.||..|:.....|...|||..|
Zfish   285 DMVARPSMGIVANTKWVRPRVQHFFAASILLN--GVCHLLAPLSTDYTGFVIYAIFFGFAFG--- 344

  Fly   535 GLTSVI---LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAIS 596
            .|:||:   |:||:|..:.::|.||:.:.:.....:|||:.|...|:...|...::..|:::.|.
Zfish   345 WLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVLLIG 409

  Fly   597 GLVMFA-----IPPLQRLQVRKSERKPHTEH 622
            .|.:|.     ...|:|  ..|.|.|...:|
Zfish   410 SLFLFVGMGINYKLLER--EAKEESKKANQH 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	66/181 (36%)
		MFS	<426..604	CDD:119392	45/189 (24%)
slc16a1a	NP_001243569.1	2A0113	6..446	CDD:273325	140/616 (23%)
		MFS	20..415	CDD:119392	126/581 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578874
Domainoid	1	1.000	142	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.850