Protein Alignment Mct1 and slc16a1a

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001243569.1
• Gene: slc16a1a / 100534752
• ZFINID: ZDB-GENE-110408-16
• Length: 461
• Species: Danio rerio
• Alignment Length: 616
• Identity: 140/616 - (22%)
• Similarity: 229/616 - (37%)
• Gaps: 209/616 - (33%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||:|||||.||.|:|    ::.|.:|:|    .:|:.|....||......:||:|||:.|.:..
Zfish    12 TPPEGGWGWAVVLGAF----ISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            ||:||..||:||.|.:.|.|..|:.:.:|.:.|...|..|...:|...|||......||:..:.:
Zfish    73 GPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..||.:|.|||:.||.......|||..:....:||||:.||:||::|||.:.|::.||:
Zfish   138 YFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPI---- 198

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
                                                                             
Zfish   199 ----------------------------------------------------------------- 198

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                             ||    .||..||:
Zfish   199 -----------------GP----KPQPAVKA---------------------------------- 208

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
                                                    .|:.|:::|              |.
Zfish   209 ----------------------------------------DNSNSRAKE--------------RK 219

  Fly   413 TFAEMMN----FSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVA 473
            |..|::|    .:|.|...|:::.:.|.....|...|.:::..||::.::.:..|::|:|.:...
Zfish   220 TVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFV 284

  Fly   474 NTVGRIILGYISDKPW----VNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYV 534
            :.|.|..:|.:::..|    |......::.|.  ||...:.||..|:.....|...|||..|
Zfish   285 DMVARPSMGIVANTKWVRPRVQHFFAASILLN--GVCHLLAPLSTDYTGFVIYAIFFGFAFG--- 344

  Fly   535 GLTSVI---LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAIS 596
            .|:||:   |:||:|..:.::|.||:.:.:.....:|||:.|...|:...|...::..|:::.|.
Zfish   345 WLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVLLIG 409

  Fly   597 GLVMFA-----IPPLQRLQVRKSERKPHTEH 622
            .|.:|.     ...|:|  ..|.|.|...:|
Zfish   410 SLFLFVGMGINYKLLER--EAKEESKKANQH 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	128/589 (22%)
slc16a1a	NP_001243569.1	MFS_MCT1	19..417	CDD:340984	128/584 (22%)