Protein Alignment Mct1 and slc16a2

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_031747020.1
• Gene: slc16a2 / 100494635
• XenbaseID: XB-GENE-980579
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 130/606 - (21%)
• Similarity: 212/606 - (34%)
• Gaps: 190/606 - (31%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFY----NEFLDYFNEGKGY-TAWIASIMVGVTFSSG 88
            |:||:|||||..:........|:..||||.|    .|......:|..: |||:.|:.:|:.|...
 Frog    52 PEGGFGWVVVLAATWCSGSIFGIQNSFGIIYVMLQGEMDGTEEQGMDFKTAWVGSLAMGMIFFCS 116

  Fly    89 PISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQY 153
            |:.|.|.:|.|||..:..|:.||...::.|.|.:::.....|.|...|.|....:.|::|.:..|
 Frog   117 PVVSIFTDRLGCRKTSSGGAALAFIGLLSSSFTKSLGVRYFTYGILFGCGCSFAFQPSLVILGHY 181

  Fly   154 FEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAP 218
            |:.:..|..|| |.|   |:.||.....||         :.::||
 Frog   182 FKKRLGLVNGI-VAG---GSCVFTMCLPFL---------LKMMGG-------------------- 213

  Fly   219 PQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHN 283
                             ||..|:|       .:||....::|:                 .:...
 Frog   214 -----------------AIGLQHT-------FQVLSVFMFIQI-----------------FLSLT 237

  Fly   284 LKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRP 348
            .||                |:.||
 Frog   238 FKP----------------LLPPP----------------------------------------- 245

  Fly   349 DALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCG---CITCSKET 410
                                                      |..|:|:.|..|   ...|...|
 Frog   246 ------------------------------------------VDFSKEKEKVAGRSKAQQCMAHT 268

  Fly   411 RDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANT 475
            |..|    |..:.:...:.|:::....|.:|:.|||::::.:.|......|....|:..||..:.
 Frog   269 RKYF----NMQVFRRKTYTIWALGIATTVLGYFVPYVHLIKFVEQRFKENTKEWVLLVCIGATSG 329

  Fly   476 VGRIILGYISDK-PWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSV 539
            :||:..|.|.|. |.:.::.:........|:.:.|:|||..|:|:...|...|...|..:.:.|.
 Frog   330 IGRLASGRIGDSIPGLKKIYLQVASFLLLGILSMMLPLCQVFESVIVVCLFLGLCDGFLISMMSP 394

  Fly   540 ILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIP 604
            |..:|:|..:.:.|.|.:|....|....||||.|.:.|...||..||.:||:...|..:|:.::|
 Frog   395 IAFELVGPMQASQAIGYVLGLMSIPMTAGPPIAGLLRDYCGSYDLAFYLAGIPPLIGAMVLLSVP 459

  Fly   605 PLQRLQVRK----SERKPHTE 621
            .:....::|    .|.|..|:
 Frog   460 LVHERDLKKKRQMEEEKEKTQ 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	50/182 (27%)
		MFS	<426..604	CDD:119392	49/178 (28%)
slc16a2	XP_031747020.1	MFS_MCT8	57..459	CDD:341023	122/578 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920