Protein Alignment Mct1 and slc16a14

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_002944264.2
• Gene: slc16a14 / 100491705
• XenbaseID: XB-GENE-6049356
• Length: 513
• Species: Xenopus tropicalis
• Alignment Length: 609
• Identity: 168/609 - (27%)
• Similarity: 278/609 - (45%)
• Gaps: 138/609 - (22%)

  Fly    10 KSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTA 74
            ||:.|.:....:::|       ||.|:||..||::|::..|...:.||...|:|:.|.:.:|.||
 Frog    17 KSKTQMKKVNPNIDR-------GWAWMVVLSSFLVHLLVMGSQMALGILNLEWLEEFKQSRGLTA 74

  Fly    75 WIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGF 139
            ||:|:.:|:|...|||...|:|..|||...:.|..|.:...::|.:|.||..|..:.|...|:|.
 Frog    75 WISSLSMGITLIVGPIIGLFINTCGCRKTAMIGGFLTSLGWVLSAYAPNVHFLFFSFGVTAGIGS 139

  Fly   140 GLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCI 204
            |::||||:|:|..||:.:|:||.|::..|:|||||:...|.::|....|||.||:|.|.:.||..
 Frog   140 GMVYLPAVVTVGHYFQKRRALAQGLSTTGTGFGTFLITVLLKYLCRELGWRNAMIIQGAVTLNLC 204

  Fly   205 IFGAMFRPLEL-EAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTA 268
            :.||:.|||:. |...:........||.||:.|:::.|...|..|    |.:::  :.....|||
 Frog   205 VCGALMRPLDHDEEHLKDHEEAAVDPKDAKEGALLNVNAIKANSE----LHEEE--EGKASADTA 263

  Fly   269 VSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLR 333
            ||..                                       |..:.:||
 Frog   264 VSWS---------------------------------------KEETRNDI-------------- 275

  Fly   334 DAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLS--RSMSGSGVIKRYGSLRQSNNVSQSQE 396
                                        :::..|.||  ::::...|..|.|
 Frog   276 ----------------------------FINDMNKLSIMKTLTHMTVSVRSG------------- 299

  Fly   397 EAKCCGCITCSKETRDTFAEMMNF----SLLKDMVFVIF---SVSNFCTSIGFNVPYLYVVAYAE 454
                            .||...::    ||..:.|||.|   ::..:|:   |.:|::::....|
 Frog   300 ----------------FFAWYSSYFGASSLFTNKVFVAFVFWALLAYCS---FVIPFIHLPEIVE 345

  Fly   455 TLKLTKTDASY-LISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQS 518
            ...||:.:..: |.|.|.:.:..|::|||::.|.|.|:...|:.......|||..::||.|.:.|
 Frog   346 MYGLTEQNNIFPLTSIIAIVHIFGKVILGFLGDLPCVSAWNVFIASNFTLGVSILILPLMHVYSS 410

  Fly   519 LAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYA 583
            ||..|.:.||:.| |..|..|:..||:|:.:|.||:|:::...||::.:|||..||:||:|..|.
 Frog   411 LALVCALIGFSSG-YFSLMPVVTEDLVGIKQLANAYGIIICANGISALLGPPFAGWIYDITQKYD 474

  Fly   584 PAFLMAGLMIAISGLVMFAIPPLQ 607
            .:|.:.||:..:..:.:...|.||
 Frog   475 YSFYVCGLLYMVGIICLLLEPCLQ 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	71/177 (40%)
		MFS	<426..604	CDD:119392	58/181 (32%)
slc16a14	XP_002944264.2	MFS_MCT14	34..495	CDD:340987	159/580 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	150	1.000	Domainoid score	I4349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2724
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm14090
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970