Protein Alignment Mct1 and slc16a5

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_002940018.3
• Gene: slc16a5 / 100485544
• XenbaseID: XB-GENE-1008043
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 131/596 - (21%)
• Similarity: 221/596 - (37%)
• Gaps: 183/596 - (30%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGP 89
            |||.|.|||:...    ::|.|::..|    ||||.:....|......|:|..||::.|..:.||
 Frog     4 PDGPWAWVVLAAV----MLTQGLSLGFPSCIGIFYTDIQTSFQASNTETSWFPSIIMAVLHAGGP 64

  Fly    90 ISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYF 154
            :.:..|.|:|||...:.|.:|....::.|.|:|.::.|.::.||..||||...:...|..:..||
 Frog    65 LCTIMVERFGCRVTVMVGGLLCGVGMVTSAFSQTIIHLYLSAGFVGGLGFCFCFQAGITVLGYYF 129

  Fly   155 EAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPP 219
            ..:|:||..:|..|:..|..::...::.|:...||||:.|:.||::|||.:.||:.||:.
 Frog   130 IRRRTLANSLASAGASIGMALWPLASQHLLETMGWRGSFLLFGGVLLNCCVCGAIMRPVR----- 189

  Fly   220 QTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNL 284
                                      .|||
 Frog   190 --------------------------SLEP----------------------------------- 193

  Fly   285 KPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPD 349
                                                  .|.:..|.|       ...:|..::.:
 Frog   194 --------------------------------------AHEKEVLAP-------EEPNGIKHKGE 213

  Fly   350 ALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTF 414
            ...||.                      .::||
 Frog   214 KTEQGK----------------------GLQRY-------------------------------- 224

  Fly   415 AEMMNFSLL-KDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGR 478
               |.|.|| :...:.|:::......:||.:|..|:|.||.:..:.:..|:.|:|.:|..|...|
 Frog   225 ---MAFDLLFRHRRYQIYALGVTWMVLGFVLPLFYLVPYATSNDIDEKKAALLLSLVGFMNIFMR 286

  Fly   479 IILGYIS-DKPWVNRLL-VYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVIL 541
            .:.|.:| .|.:..||: :::|.:...|:|..:..:...|.:|..||.::..|:.....|...:|
 Frog   287 PMAGLVSQQKVFHGRLMYLFSVAVILNGLSNLVCAIWVSFPALLTYCVLYSITMSFIGSLIFQVL 351

  Fly   542 VDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPL 606
            :|.:|:.:...||||..:.:.|....|||:.|.:.|:|..|...|..:.:.:..|||.|    .|
 Frog   352 MDTVGMKRFPGAFGLFTILESITIMAGPPLAGLLVDITGQYGLVFYASSIAVTSSGLFM----GL 412

  Fly   607 QRLQVRKSERK 617
            ....|.:||.|
 Frog   413 ASFAVDRSEAK 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	58/181 (32%)
		MFS	<426..604	CDD:119392	48/179 (27%)
slc16a5	XP_002940018.3	MFS_MCT6	9..414	CDD:340983	123/580 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9525
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920