Protein Alignment Nmd3 and Nmd3

DIOPT Version :10

• Sequence 1: NP_477332.1
• Gene: Nmd3 / 31195
• FlyBaseID: FBgn0023542
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_598548.1
• Gene: Nmd3 / 97112
• MGIID: 2140103
• Length: 503
• Species: Mus musculus
• Alignment Length: 496
• Identity: 263/496 - (53%)
• Similarity: 352/496 - (70%)
• Gaps: 16/496 - (3%)

  Fly    25 ILCCECGVAIQPNPANMCVTCLRNHVDITENIPKQAVLHFCRNCERYLQPPNEWIQAALESRELL 89
            ||||||||.|.|||||:||.|||:.|||::.:|||..:.||:.|:||.|||..|:|.||||||||
Mouse    15 ILCCECGVPISPNPANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELL 79

  Fly    90 AICLKKLKG-LKEVKLVDAGFIWTEQHSKRIKVKLTVHGEIIGGTMLQQVFVVEFTVQNQMCNDC 153
            |:||||:|. |.:|:||||||:|||.||||:|||||:..|::.|.:|||||||::.||:|||.||
Mouse    80 ALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDC 144

  Fly   154 HRTEAKDFWRCLVQVRQRAENKKTFYYLEQLILKHKAHENTLGIKPEHGGLDFFYANDNHARRMV 218
            ||.||||||:.::||||:..:|||||||||||||:..|:|||.||..|.||||:|::..||::||
Mouse   145 HRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMV 209

  Fly   219 DFLLTMVPGKVTTSKRLISHDIHSNNYNYKYNWSVEIAPVSKDSAVCLSKKLRHQLGNLSPLVLV 283
            :||..:||.:...|:||||.|||||.||||..:||||.|:.||:.||||.||...|||:|.:.:.
Mouse   210 EFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICIC 274

  Fly   284 NRVSSSIHLIDPLTAQIAELTSQVYFRAPFEAVCNPKQLVEYVVMDIDVIMEKDRKTYPGQGQVS 348
            .||:|:||||||.|.|:|::....::..||.::|:||||.|::|::...:  :|.|...|.|.:|
Mouse   275 IRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTV--RDLKRSAGAGVIS 337

  Fly   349 FKHALCDIWVVRASELGINDNPIHTRSHLGHLLKVGDSVMGYNTGEANINDLEFDKLSSDEIPDV 413
            .||.|.::|:.:.||:. .|.....|:||||||..||.|:|::....|:||...:|::||.:|||
Mouse   338 KKHTLGEVWIQKTSEMN-TDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDV 401

  Fly   414 ILVRKHYDRQTRLSQRVWKIKHLA-----AEATDERSKYDYHEFLDDLEENEDIRGQVNIYRDTN 473
            :|::|.|||..|..:|.||:|.||     .:..|||   .|.:||:||||:|.||..||||||.
Mouse   402 VLIKKSYDRTKRQRRRNWKLKELARDRENMDTDDER---QYQDFLEDLEEDEAIRKHVNIYRDA- 462

  Fly   474 KTIPIEVQAAGGDVPQITLEEMLEDMTLECADDEMGEEGGA 514
             |||:|........|:|:|.|||||  |..:.|..||||.:
Mouse   463 -TIPVESDTDDEGAPRISLAEMLED--LHISQDATGEEGAS 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmd3	NP_477332.1	NMD3	27..255	CDD:461505	144/228 (63%)
Nmd3	NP_598548.1	NMD3	17..246	CDD:461505	145/229 (63%)
		Nuclear and nucleolar localization signal. /evidence=ECO:0000250|UniProtKB:Q96D46	405..422		7/16 (44%)
		Necessary for the nuclear export of the 60S ribosomal subunit. /evidence=ECO:0000250|UniProtKB:Q96D46	425..503		38/82 (46%)
		Nuclear export signal. /evidence=ECO:0000250|UniProtKB:Q96D46	480..489		6/8 (75%)