Protein Alignment Cyp4ae1 and ERG5

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 100/481 - (20%)
• Similarity: 184/481 - (38%)
• Gaps: 91/481 - (18%)

  Fly    55 DNLHDKFAEYVKRFGRSFMGTV-LGHVVMVTAEPRHI-DALLQGQHQLKKGTMYFALR-----GW 112
            ::|..||.||..::....:..| :.|..:|.|..|.: ..:||....:|...:..|::     .|
Yeast    87 ESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNW 151

  Fly   113 LGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVG- 176
                 :...||.....||.:...|....|.|::...::.....:::...||..|   |..|.|.
Yeast   152 -----VFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKEN---NYEPQVFF 208

  Fly   177 ------LAALDI-------ITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPH--- 225
                  |.||.:       |||..:....|    |..:|.|..:|.|.        .::.|:
Yeast   209 HEMREILCALSLNSFCGNYITEDQVRKIAD----DYYLVTAALELVNF--------PIIIPYTKT 261

  Fly   226 ------------LFRLCWPSGFRKQQAG--VICLHEFTNGIIEQRRRLL--AREANQDKPTKPHA 274
                        :|..|.........||  .:|       :::...:|:  |:.:|.|.....|
Yeast   262 WYGKKTADMAMKIFENCAQMAKDHIAAGGKPVC-------VMDAWCKLMHDAKNSNDDDSRIYH- 318

  Fly   275 LLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYG 339
                        :..|:|:|.:.|.||:|...|.::|...:...:::....|..|:.||......
Yeast   319 ------------REFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRN 371

  Fly   340 QDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGY-IPVGTNVVVLLWQLL 403
            .|:...:.|.....:.|.:.|:||:||..||:..|...::|:..:...| .|.|..::..|:..|
Yeast   372 NDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPAL 436

  Fly   404 RDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIR----HY 464
            .|..::.:|..|.|||.:.......:..:::.|..||..|:||.:.::....::.|...    |:
Yeast   437 HDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHH 501

  Fly   465 QLLPMG------ADVEPSIKIVLRSK 484
            .:.|:.      |.:.|...::|..|
Yeast   502 TVTPLSEKIKVFATIFPKDDLLLTFK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	100/481 (21%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	93/458 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I1557
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I1313
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
TreeFam	0	0.000	Not matched by this tool.
	4	3.960