DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ae1 and CYP86A7

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_176558.1	Gene:	CYP86A7 / 842675	AraportID:	AT1G63710	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	129/540 - (23%)
Similarity:	230/540 - (42%)	Gaps:	90/540 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLVALLVTRLVASLFRLALKELRHPLQG--VVPSVSRVP-LLGAAWQMRSFQPDNLHDKFAEY-V 65
            :::.|:||.::..:      .||...:|  |.|.|..:| |:..|.:|..|..|||......| .
plant     8 IILTLIVTYIIWFV------SLRRSYKGPRVWPLVGSLPALITNAHRMHDFIADNLRMCGGTYQT 66

  Fly    66 KRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQ-HQLKKGTMYFAL-RGWLGDGLLLSRGKEWHTM 128
            ..|...|:....|||. ||.:|::::.:|:.: ....||..:.:: ...||||:..|.|..|...
plant    67 CIFPIPFLAKKQGHVT-VTCDPKNLEHILKTRFDNYPKGPSWQSVFHDLLGDGIFNSDGDTWRFQ 130

  Fly   129 RKIITPTFHFSILEQFV-----------------------EVFDRQSSIL---VERLRTLSYGNE 167
            ||.....|....|.|.:                       |..|.|..:|   .:.:..|::|.:
plant   131 RKTAALEFTTRTLRQAMARWVDRAIKNRLVPILESARSRAEPIDLQDVLLRLTFDNICGLTFGKD 195

  Fly   168 VVNI---YPLVGLA-ALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFR 228
            ...:   :|..|.| |.|..||..:                         .||:.|..::.  .|
plant   196 PRTLSPEFPENGFAVAFDGATEATL-------------------------QRFIMPEFIWK--IR 233

  Fly   229 LCWPSGFRKQQAGVIC-LHEFTNGIIEQRR-RLLAREANQDKPTKPHALLDTLLRATVDGQPLTD 291
            .....|.....:..|. :..:.:.||..|: .||.::.::.:..      |.|.|.....:..:|
plant   234 KWLRLGLEDDMSRSISHVDNYLSEIINTRKLELLGQQQDESRHD------DLLSRFMKKKESYSD 292

  Fly   292 KQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEEL--------RMHYGQDLFRGVIL 348
            |.::.....||..|.||::.|:|:..:|:|.:..|::|:..|:        ..:..:.....:..
plant   293 KYLKYVALNFILAGRDTSSVAMSWFFWLVSLNPRVEEKIINEICTILIKTRDTNVSKWTDEPLTF 357

  Fly   349 SDFATLPYLSCVVKESLRLYPPIPAVAR-CLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TD 411
            .:...|.||...:.|:|||||.:|..:: .:..|::.|..::|.|:||...::.:.|.:.|: .|
plant   358 DEIDQLVYLKAALSETLRLYPSVPEDSKFVVANDVLPDGTFVPSGSNVTYSIYSVGRMKFIWGED 422

  Fly   412 PLVFQPERHLGEEA-PRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKV-IRHYQLLPMGADVE 474
            .|.|:|||.|.|.. .:.:.|.::.|:||||.|:|:..|.|:||::...: :||...:..|..||
plant   423 CLEFKPERWLEESRDEKCNQYKFVAFNAGPRICLGKDLAYLQMKSITASILLRHRLTVAPGHRVE 487

  Fly   475 PSIKIVLRSKSGVNVGLRPR 494
            ..:.:.|..|.|:.:.:..|
plant   488 QKMSLTLFMKFGLKMDVHKR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	120/498 (24%)
CYP86A7	NP_176558.1	PLN03195	4..507	CDD:215627	128/538 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910