DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	116/458 - (25%)
Similarity:	200/458 - (43%)	Gaps:	80/458 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 VMVTAEPRHIDALLQGQHQ-LKKGTMYFA-LRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQ 143
            :::||.|.:::.:|:.:.: ..||..:.: |..:||.|:..|.|..|...||..:..|....|..
plant    76 LIMTANPSNVEYMLKTKFESFPKGQQFTSVLEDFLGHGIFNSDGDMWWKQRKTASYEFSTKSLRD 140

  Fly   144 F------VEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEV- 201
            |      ||:..|...:|||...|    .:::::..::...|.|.|.:.|..|:....|.|..|
plant   141 FVMSNVTVEINTRLVPVLVEAATT----GKLIDLQDILERFAFDNICKLAFNVDCACLGHDGAVG 201

  Fly   202 ---VHAVKDLTNILATRFMRPHLLFPHLFRLCWP-------SGFRKQQAGVICLHEFTNGIIEQR 256
               :.|.:....|::.||.       .:....|.       ...|..:..:..:|:|.:.|:..|
plant   202 VNFMRAFETAATIISQRFR-------SVASCAWRIKKKLNIGSERVLRESIATVHKFADEIVRNR 259

  Fly   257 ----------RRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTS 311
                      ..||:|..::::...|..|                   ||.|.:||..|.|||:|
plant   260 IDQGRSSDHKEDLLSRFISKEEMNSPEIL-------------------RDIVISFILAGRDTTSS 305

  Fly   312 AVSFCLYLLSRHEAVQQKLFEEL---RMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPA 373
            |:|:..:|||.|..|:.|:.:||   |...|:.:...........:.||...:.||||||||:|.
plant   306 ALSWFFWLLSMHPEVEDKILQELNSIRARTGKRIGEVYGFEHLKMMNYLHAAITESLRLYPPVPV 370

  Fly   374 -VARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHL--------GEEAPRL 428
             :..|.|.:::.|..::..|..:...::.:.|.|:|: .|...|.|||.:        ||:
plant   371 DIKSCAEDNVLPDGTFVGKGWAITYNIFAMGRMESIWGKDCDRFDPERWIDETNGCFRGED---- 431

  Fly   429 SPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSI--KIVLRSKSGVNVGL 491
             |..:..|.||||.|:|:..|.::||::|..|:..:.:...|.: .|.|  .:.||.|.|:...:
plant   432 -PSKFPAFHAGPRMCVGKDMAYIQMKSIVAAVLERFVVEVPGKE-RPEILLSMTLRIKGGLFARV 494

  Fly   492 RPR 494
            :.|
plant   495 QER 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	114/448 (25%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	114/449 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910