DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP86A4

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_171666.1	Gene:	CYP86A4 / 839347	AraportID:	AT1G01600	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	578	Identity:	135/578 - (23%)
Similarity:	225/578 - (38%)	Gaps:	161/578 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVKRFGRSF 72
            |:|:..:|.. :.|..|.:...|:|  |.|  .||||:...:.. |.|.:|:...|.::..|.::
plant     6 AMLLVAIVTG-YWLWFKRISRWLKG--PRV--WPLLGSLPGLIE-QRDRMHEWITENLRACGGTY 64

  Fly    73 MGTVLG--------HVVMVTAEPRHIDALLQGQHQLK-------KG-TMYFALRGWLGDGLLLSR 121
            ...:..        .:|.||.:|:::      :|.||       || |........||.|:..|.
plant    65 QTCIFAVPFLAKKQGLVTVTCDPKNL------EHMLKTRFDNYPKGPTWQSVFHDLLGQGIFNSD 123

  Fly   122 GKEWHTMRKIITPTFHFSILEQFV-----------------------EVFDRQSSIL---VERLR 160
            |..|...||.....|....|.|.:                       |..|.|..||   .:.:.
plant   124 GDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILATAQDNAEPVDLQDLILRLTFDNIC 188

  Fly   161 TLSYGNEVVNIYPLVGL------AALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRP 219
            .|::|.:.....|  ||      :|.|..||.::                         .||:.|
plant   189 GLAFGKDTRTCAP--GLPENGFASAFDRATEASL-------------------------QRFIIP 226

  Fly   220 HLLFPHLFRLCWPSGFRKQQAGVIC----------LHEFTNGIIEQRRRLLAREANQDKPTKPHA 274
                    :..|.   .|:..|:..          :.|:...:|..|::.|.  :.|:..|  |.
plant   227 --------KFMWK---LKKWLGLGLEVSLSRSLGEIDEYLAAVINTRKQELM--SQQESGT--HQ 276

  Fly   275 LLDTLLRATV--DGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMH 337
            ..|.||...:  ..:..:|..::.....||..|.||::.|:|:..:|::.|..|:.|:..|:
plant   277 RHDDLLSRFMMKKTESYSDTFLQHVALNFILAGRDTSSVALSWFFWLITMHPTVEDKIVREI--- 338

  Fly   338 YGQDLFRGVILSDFAT------------------LPYLSCVVKESLRLYPPIPAVARCLEKDLVI 384
                  ..|::....|                  |.||...:.|:|||||.:|..::.:|.|.|:
plant   339 ------CSVLIETRGTDDVASWTEEPLGFDEIDRLVYLKAAISETLRLYPSVPEDSKHVENDDVL 397

  Fly   385 DEG-YIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHLGEEAPRLSP----------YSYIPFS 437
            .:| ::|.|::|...::...|.::.: .|.|.|.|||.       :||          |.::.|:
plant   398 PDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFNPERW-------ISPIDGKFINHDQYRFVAFN 455

  Fly   438 AGPRNCIGQKFALLEMKTMVTKV-IRHYQLLPMGADVEPSIKIVLRSKSGVNVGLRPR 494
            ||||.|:|:..|.|:|||:...| :||...:..|..||..:.:.|..|:|:.|.|..|
plant   456 AGPRICLGKDLAYLQMKTIAAAVLLRHRLTVVPGHKVEQKMSLTLFMKNGLLVNLYKR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	124/541 (23%)
CYP86A4	NP_171666.1	PLN03195	5..513	CDD:215627	134/576 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910