DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ae1 and CYP77B1

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_172626.1	Gene:	CYP77B1 / 837704	AraportID:	AT1G11600	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	118/511 - (23%)
Similarity:	218/511 - (42%)	Gaps:	93/511 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVKRFGRSF---MGTVLGHVVMVTAEPRHIDALL 94
            :.|.....||:|...|: .||..:......:..|::|..|   ||.  ..::::|.|....:||:
plant    35 IPPGPKGWPLVGNLLQV-IFQRRHFVFLMRDLRKKYGPIFTMQMGQ--RTMIIITDEKLIHEALV 96

  Fly    95 QGQHQLKKGTMYFA------LRGWLGDGLLLSRGK----------EWHTMRK-IITPTFHFSILE 142
            |      :|..:.:      :|      |:.|.||          .|.|:|: .:|.......::
plant    97 Q------RGPTFASRPPDSPIR------LMFSVGKCAINSAEYGSLWRTLRRNFVTELVTAPRVK 149

  Fly   143 Q--FVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEVVHAV 205
            |  ::..:..|:.  ::|::|.:.....|.:.....|....|:.....|..:..:        .:
plant   150 QCSWIRSWAMQNH--MKRIKTENVEKGFVEVMSQCRLTICSILICLCFGAKISEE--------KI 204

  Fly   206 KDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQ--------QAGVICLHEFTNGIIEQRRRLL-A 261
            |::.|:|....:......|....:..|. ||:|        :..:.||..    :|..||:.: |
plant   205 KNIENVLKDVMLITSPTLPDFLPVFTPL-FRRQVREARELRKTQLECLVP----LIRNRRKFVDA 264

  Fly   262 REANQDKPTKP--HALLDTLLRATV--DGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSR 322
            :|...::...|  .|.:|:|.|..:  .|..|.|::|....:..:..|.||:.:.:.:.|:.|..
plant   265 KENPNEEMVSPIGAAYVDSLFRLNLIERGGELGDEEIVTLCSEIVSAGTDTSATTLEWALFHLVT 329

  Fly   323 HEAVQQKLFEELRMHYGQDLFRGVI-LSDFATLPYLSCVVKESLRLYPPIP-AVARCLEKDLVID 385
            .:.:|:||:||:....|::   ||: ..|.|.:|||..:|||:||.:||.. .::....||..:.
plant   330 DQNIQEKLYEEVVGVVGKN---GVVEEDDVAKMPYLEAIVKETLRRHPPGHFLLSHAAVKDTELG 391

  Fly   386 EGY-IPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHL----GEEAPRLSP--YSYIPFSAGPRNC 443
             || ||.|..|.:....:..:..|::||..|:|||.|    |.:|.....  .:.:||.||.|.|
plant   392 -GYDIPAGAYVEIYTAWVTENPDIWSDPGKFRPERFLTGGDGVDADWTGTRGVTMLPFGAGRRIC 455

  Fly   444 IGQKFALLEMKTMVTKVIRHYQLLPMGADVEP--------------SIKIVLRSKS 485
            ......:|.:..|:.::|..::.:|: .|..|              |:|..:||::
plant   456 PAWSLGILHINLMLARMIHSFKWIPV-PDSPPDPTETYAFTVVMKNSLKAQIRSRT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	118/509 (23%)
CYP77B1	NP_172626.1	CYP77_89	68..503	CDD:410698	107/468 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000