DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and AT5G08250

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001330676.1	Gene:	AT5G08250 / 830721	AraportID:	AT5G08250	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	126/531 - (23%)
Similarity:	237/531 - (44%)	Gaps:	67/531 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYV- 65
            ::.|.:|..|...:.|     |::.:|....|.|.|..:|.|.:|  :||    |:::..::.:
plant    39 ILELFIAFFVFATIHS-----LRQKKHQGMPVWPLVGMLPSLISA--VRS----NIYEWLSDVLI 92

  Fly    66 -----KRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYF--ALRGWLGDGLLLSRGK 123
                 .||...:..|:   ..:||.:||:::.||:.:..:.....||  .::..||||:..:...
plant    93 SQNGTFRFRGPWFSTL---NCVVTCDPRNVEHLLKTRFSIYPKGSYFRETMQDLLGDGIFNTDDG 154

  Fly   124 EWHTMRKIITPTFHFSILEQFVEVFDRQS--SILVERLRTLSYGNEVVNIYPLVGLAALDIITET 186
            .|...||..:..||.:...|...    ||  .::..||..:...:..:::..::.....|.:...
plant   155 TWQRQRKAASVEFHSAKFRQLTS----QSLHELVHNRLLPVLETSGKIDLQDILLRLTFDNVCMI 215

  Fly   187 AMGVN---VDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEF 248
            |.||:   :..:..:.....|.:|.|.....||:.|..:: .|.|.......:|.:..:..:.:|
plant   216 AFGVDPGCLSPKLPEIPFAKAFEDATEATVVRFVMPKFVW-KLMRSLNLGTEKKLKESINGVDDF 279

  Fly   249 TNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAV 313
            ...:|..|::.::.|....|  :|..|...:.....:||..:||.:||....||..|.||::.|:
plant   280 AEEVIRTRKKEMSLETEIAK--RPDLLTIFMGLRDENGQKFSDKFLRDICVNFILAGRDTSSVAL 342

  Fly   314 SFCLYLLSRHEAVQQKLFE------ELRMHYG--------QDLFRGVILSDFATLPYLSCVVKES 364
            |:..:|:.::..|::|:..      |.|:.:|        :.:||.   .:...:.||...:.|:
plant   343 SWFFWLIEKNPEVEEKIMMGICKILEQRVDHGDTKKNMEYEPVFRP---EEIKKMDYLQAALSET 404

  Fly   365 LRLYPPIPAVAR-CLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPE------RHL 421
            |||||.:|...: .||.|:..|...:..|..|:..::.:.|.|.|: .|...|:||      |::
plant   405 LRLYPSVPVDHKEVLEDDVFPDGTKLKKGEKVIYAIYAMGRMETIWGKDCREFKPERWLRDGRYM 469

  Fly   422 GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLL---PMGADVEPSIKIVLRS 483
            .|.|     |.:..|:.|||.|:|:.||..:|:.:...:|..|::.   ..|..|||.:.:.:..
plant   470 SESA-----YKFTAFNGGPRLCLGKDFAYYQMRYVAAAIIYRYKVRVDDKGGHKVEPKMALTMYM 529

  Fly   484 KSGVNVGLRPR 494
            |.|:.|.:..|
plant   530 KHGLKVNMVKR 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	116/488 (24%)
AT5G08250	NP_001330676.1	CYP86A	98..533	CDD:410687	108/452 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910