DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP96A12

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_195661.1	Gene:	CYP96A12 / 830105	AraportID:	AT4G39510	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	443	Identity:	105/443 - (23%)
Similarity:	190/443 - (42%)	Gaps:	44/443 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 VMVTAEPRHIDALLQGQ-HQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQF 144
            ::.|.:|.:|..:|... ....||..:..:....|:.:..|..:.|...||          ..||
plant    78 MLFTVDPANIHYILSSNFSNYTKGADFKEVFDVFGEMIFSSDSELWKNQRK----------AAQF 132

  Fly   145 VEVFDRQSSILVERLRTLSYG------------NEVVNIYPLVGLAALDIITETAMGV---NVDA 194
            :........:.:...|:..|.            .:||::..:......|.......|.   ::..
plant   133 MLNHQGFQKLSLSATRSKLYDGLVPLFNQCCEEEKVVDLQQVFQRFTFDTTFFIVTGFDPKSLSI 197

  Fly   195 QGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRL 259
            :..:.|...|:.||...:..|.::|...:....|.......|..:|...........|:.:|..:
plant   198 EMPEVEYAKALDDLGEGIFYRHIKPKFFWKLQNRFGLGQEKRMTEADATFDRVSAKYILAKREEI 262

  Fly   260 ----LAREAN---QDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCL 317
                :...||   :|..|. |..|||.....::  |..||.:||.:..|...|.|||:||:|:..
plant   263 RSQGIDHHANGESEDLLTS-HIKLDTTKYELLN--PSDDKFLRDTILAFNLAGRDTTSSALSWFF 324

  Fly   318 YLLSRHEAVQQKLFEE-LRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKD 381
            :|||.:..|..|:.:| :..:..:|...|  ..:...|.||...:.||:|||||:....:...|.
plant   325 WLLSENPQVVTKIRKEIIDKNISKDGRNG--QENLDKLVYLHAALYESMRLYPPVAFQRKSPIKP 387

  Fly   382 LVIDEGY-IPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHLGEEAP-RLSP-YSYIPFSAGPRN 442
            .|:..|: :...:.:::.|:.|.|..|:: .|...|:|||.:.|... |.:| :.::.|:||||.
plant   388 DVLPSGHKVEANSVIIIFLFALGRMRAVWGEDATEFKPERWVSESGGLRHAPSFKFLSFNAGPRT 452

  Fly   443 CIGQKFALLEMKTMVTKVIRHYQL-LPMGADVEPSIKIVLRSKSGVNVGLRPR 494
            |.|::.|:..|||:|.:::::|.: :..|..:||...::|..|.|:.|.:..|
plant   453 CPGKQLAMTLMKTVVVEILQNYDIDVIKGQKIEPEPGLMLHMKHGLRVTITKR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	102/433 (24%)
CYP96A12	NP_195661.1	CYP86A	66..498	CDD:410687	102/434 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910