DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ae1 and CYP78A9

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001190156.1	Gene:	CYP78A9 / 825361	AraportID:	AT3G61880	Length:	555	Species:	Arabidopsis thaliana

Alignment Length:	564	Identity:	141/564 - (25%)
Similarity:	222/564 - (39%)	Gaps:	118/564 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLVALL------------VTRLVASLFRLALKEL--RHP--------------LQGVVPSVSRVP 41
            ||:|||            ::.|||||..|||...  .||              ...|:|....:|
plant    10 LLLALLSKCSLLTQTNLALSLLVASLASLALSLFFWSHPGGPAWGKYFLHRRRQTTVIPGPRGLP 74

  Fly    42 LLGAAWQMRSFQPDNL-HDKFAEYVKRF-GRSFMGTVLGHV-VMVTAEPRHIDALLQ----GQHQ 99
            .:|:    .|...:.| |...|...::| ....|...||.. |:||..|.....:|.    ....
plant    75 FVGS----MSLMSNTLAHRCIAATAEKFRAERLMAFSLGETRVIVTCNPDVAKEILNSPVFADRP 135

  Fly   100 LKKGTMYFALRGWLGDGLLLSRGKEWHTMRKII------------TPTFHFSILEQFVEVFDRQS 152
            :|:..........:|   ....|..|.|:|||.            :.|....|..|.|:...:||
plant   136 VKESAYSLMFNRAIG---FAPYGVYWRTLRKIASNHLFSPKQIKRSETQRSVIANQIVKCLTKQS 197

  Fly   153 SILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEVVHAVKDLT----NILA 213
            :     .:.|.:..:      |:..|:|:.:..:..|...:.: .:.|.|..:::|.    ::|.
plant   198 N-----TKGLCFARD------LIKTASLNNMMCSVFGKEYELE-EEHEEVSELRELVEEGYDLLG 250

  Fly   214 TRFMRPHLLFPHLFRLCWPSGFRKQQAGVIC------LHEFTNGIIEQRRRLLAREANQDKPTKP 272
            |.....||  |      |.|.|..|:....|      ::.|.|.||...     ||..:|.|:.
plant   251 TLNWTDHL--P------WLSEFDPQRIRSRCSNLVPKVNRFVNRIISDH-----REQTRDSPSD- 301

  Fly   273 HALLDTLLRATVDG-QPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRM 336
              .:|.||  ::|| ..|:|..|...:...||.|.||....:.:.|..:..|..:|..:..||..
plant   302 --FVDVLL--SLDGPDKLSDPDIIAVLWEMIFRGTDTVAVLIEWILARMVLHPDIQSTVHNELDQ 362

  Fly   337 HYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAV--ARCLEKDLVIDEGYIPVGTNVVVLL 399
            ..|:.  |.|..||..:|.||:.||||.|||:||.|.:  ||....|.:||...:|.||..:|.:
plant   363 IVGRS--RAVEESDVVSLVYLTAVVKEVLRLHPPGPLLSWARLAITDTIIDGRRVPAGTTAMVNM 425

  Fly   400 WQLLRDEAIFTDPLVFQPERHLGEEAP----------RLSPYSYIPFSAGPRNCIGQKFALLEMK 454
            |.:..|..::.:||.|:|||.:.:|..          ||:     ||.:|.|.|.|:...|..:.
plant   426 WAIAHDPHVWENPLEFKPERFVAKEGEVEFSVLGSDLRLA-----PFGSGRRVCPGKNLGLTTVT 485

  Fly   455 TMVTKVIRHYQLLPMG----ADVEPSIKIVLRSKSGVNVGLRPR 494
            .....::..::.|...    .|:...:::.....:.:...||||
plant   486 FWTATLLHEFEWLTPSDEKTVDLSEKLRLSCEMANPLAAKLRPR 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	121/496 (24%)
CYP78A9	NP_001190156.1	p450	56..529	CDD:299894	124/516 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000