DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP86C2

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_189243.1	Gene:	CYP86C2 / 822212	AraportID:	AT3G26125	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	124/499 - (24%)
Similarity:	223/499 - (44%)	Gaps:	66/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 WQMRSFQPD---NLHDKFAEYVKRFGRSFMGT-------VLGHVVMVTAEPRHIDALLQGQHQ-L 100
            |.:....|:   ::||.|. :|.|......||       ..|....:|:.|.:|:.:|:...: .
plant    49 WPVFGITPEFFLHVHDMFG-WVTRCLTKSRGTFPYQGIWFSGSYGAMTSVPANIEYMLKTNFKNF 112

  Fly   101 KKGTMY-FALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVER-----L 159
            .||..| ...|..|.||:..:..:.|...|:||....|.:   :||:...:.:..|:||     :
plant   113 PKGEFYKERFRDLLEDGIFNADDESWKEQRRIIITEMHST---RFVDHSFQTTRDLIERKLLKVM 174

  Fly   160 RTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGA-DSEVVH-----AVKDLTNILATRFMR 218
            .:.|...|..::..::.....|.|....:|   |..|. |.::.|     |.::.|.....|||.
plant   175 ESFSKSQEAFDLQEILLRLTFDNICIAGLG---DDPGTLDDDLPHVPFAKAFEEATESTLFRFMI 236

  Fly   219 PHLLFPHL--FRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLR 281
            |..::..:  |.:.:..|.|:   .|..:|.|.:.::.:|..:|     :|:.|..::..|.|.|
plant   237 PPFVWKPMKFFDIGYEKGLRE---AVETVHNFIDKMVVERIAML-----KDQGTLANSKSDVLSR 293

  Fly   282 ATV--------DGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHY 338
            ...        :....|.|..|....:||..|.||::.|:::..:|:::|..|:.|:..|:|...
plant   294 LIQIESHKRGDENDRFTAKFFRQFCTSFILAGRDTSSVALTWFFWLITKHPEVETKILHEIREIL 358

  Fly   339 GQ--------------DLFRGVILSDFATLPYLSCVVKESLRLYPPIP-AVARCLEKDLVIDEGY 388
            .|              :..|...:.:...:.||...:.|||||||||| .:.:..|:|:..|..:
plant   359 NQREKNKYKLDETGEKESSRHFTVKELNDMVYLQAALSESLRLYPPIPMEMKQATEEDVFPDGTF 423

  Fly   389 IPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHL-GEEAPRLSPYSYIPFSAGPRNCIGQKFALL 451
            :..|:.|...::.:.|.|:|: .|..:|:|||.: |.:......:.|:.|:||||.|:|:.||.|
plant   424 LRKGSRVYFSVYAMGRMESIWGKDCEMFKPERWIQGGQYVSDDQFKYVVFNAGPRLCLGKTFAYL 488

  Fly   452 EMKTMVTKVIRHYQL-LPMGADVEPSIKIVLRSKSGVNVGLRPR 494
            :||.:...::.:|.: :.....|.|.:...|..|.|:.|.:.||
plant   489 QMKMVAASILLNYSIKVDQDHVVVPRVTTTLYMKHGLKVRITPR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	120/489 (25%)
CYP86C2	NP_189243.1	PLN03195	42..533	CDD:215627	124/499 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910