DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ae1 and CYP89A9

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_186997.1	Gene:	CYP89A9 / 821250	AraportID:	AT3G03470	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	123/571 - (21%)
Similarity:	225/571 - (39%)	Gaps:	139/571 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLVVLLVALLVTRLVASLF-RLALKELRHPLQGVVPSVSRVPLLG-AAWQMRSFQPDNLHDKFAE 63
            |.:..::.|:::.|..|:| :|......|.|.   |...|.|::| ..|..:        :.|::
plant     1 MEITTIIFLIISSLTFSIFLKLIFFFSTHKLP---PGPPRFPVIGNIIWLKK--------NNFSD 54

  Fly    64 Y--VKRFGRSFMGTVLG-HV-----VMVTAEPRHIDALLQ--------------------GQHQL 100
            :  |.|...|..|.::. ||     :.||.......||:|                    .||.:
plant    55 FQGVLRDLASRHGPIITLHVGSKPSIWVTDRSLAHQALVQNGAVFSDRSLALPTTKVITSNQHDI 119

  Fly   101 KKGTMYFALRGWLGDGLLLSRGKEWHTMRKIIT-------------PTFHFSILEQFVEVFD--- 149
             ..::|               |..|.|:|:.:|             |:..:| ||..|::|:
plant   120 -HSSVY---------------GSLWRTLRRNLTSEILQPSRVKAHAPSRKWS-LEILVDLFETEQ 167

  Fly   150 RQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILAT 214
            |:...:.:.|..|.:.     ::.|:.|...             .:....|.:..:::....:..
plant   168 REKGHISDALDHLRHA-----MFYLLALMCF-------------GEKLRKEEIREIEEAQYQMLI 214

  Fly   215 RFMRPHLL--FP----HLFRLCWPS--GFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTK 271
            .:.:..:|  ||    .|.|..|..  ..||.|..||.  .:.|.              :.|.|.
plant   215 SYTKFSVLNIFPSVTKFLLRRKWKEFLELRKSQESVIL--RYVNA--------------RSKETT 263

  Fly   272 PHAL--LDTLLRATV-----DG---QPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAV 326
            ...|  :||||...:     :|   :.|:|.:|....:.|:....|.|.:::.:.:.::.::..:
plant   264 GDVLCYVDTLLNLEIPTEEKEGGKKRKLSDSEIVSLCSEFLNAATDPTATSMQWIMAIMVKYPEI 328

  Fly   327 QQKLFEELRMHY-GQDLFRGVIL-SDFATLPYLSCVVKESLRLYPPIPAVA-RCLEKDLVIDEGY 388
            |:|::||::..: |::..|..|. .|...|.||..|:.|.||.:||...:: ..:..|.|:....
plant   329 QRKVYEEMKTVFAGEEEEREEIREEDLGKLSYLKAVILECLRRHPPGHYLSYHKVTHDTVLGGFL 393

  Fly   389 IPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHL--GE----EAPRLSPYSYIPFSAGPRNCIGQK 447
            ||....:..::.::.||..|:.|||.|:|||.|  ||    :.........:||.||.|.|.|..
plant   394 IPRQGTINFMVGEMGRDPKIWEDPLTFKPERFLENGEACDFDMTGTREIKMMPFGAGRRMCPGYA 458

  Fly   448 FALLEMKTMVTKVIRHYQLLPM-GADVEPSIK---IVLRSKSGVNVGLRPR 494
            .:||.::..|..::..::...: |.:|:.|.|   |.:..|:.....:.||
plant   459 LSLLHLEYYVANLVWKFEWKCVEGEEVDLSEKQQFITMVMKNPFKANIYPR 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	113/526 (21%)
CYP89A9	NP_186997.1	CYP77_89	65..503	CDD:410698	104/488 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000