DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	123/513 - (23%)
Similarity:	219/513 - (42%)	Gaps:	73/513 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LVVLLVALLVTRLV------ASLFRLALKELRHPLQGVVPSVSRVPLLG-------AAWQMRSFQ 53
            ::|.:|.|...|:|      ..:...:||.     ||:. .....||:|       ...:.|| :
plant    11 VLVAVVVLWTWRIVKWVWIKPKMLESSLKR-----QGLT-GTPYTPLVGDIKRNVDMMMEARS-K 68

  Fly    54 PDNLHDKFA--------EYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALR 110
            |.|:.|...        :.:...|::|...:.....:|...|..|..:....:..:|.:.:..:|
plant    69 PINVTDDITPRLLPLALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEVFNKVNDFEKASTFPLIR 133

  Fly   111 GWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILV---ERLRTLSYGNEVVNIY 172
             .|..||...:|.:|.:.|:||.|.||...::..:..|....|.:|   |:|.|.......|:::
plant   134 -LLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKESPLEVDVW 197

  Fly   173 P-LVGLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHL----LFPHLFRLCWP 232
            | ||.:.| |:|:.||.|   .:......:.....:|..::|..|.:.::    .:|       .
plant   198 PWLVNMTA-DVISHTAFG---SSYKEGQRIFQLQGELAELIAQAFKKSYIPGSRFYP-------T 251

  Fly   233 SGFRKQQAGVICLHEFTNGIIEQRRRLLARE----ANQDKPTKPHALLDTLLRATVD---GQPLT 290
            ...|:.:|....:.....||:.:|.:  |||    ||.|       ||..||.:..:   |..::
plant   252 KSNRRMKAIDREVDVILRGIVSKREK--AREAGEPANDD-------LLGILLESNSEESQGNGMS 307

  Fly   291 DKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLP 355
            .:.:..|...|.|.|.:||:..:.:.:.|||.|:..|.:..||:....|::  ....:.....|.
plant   308 VEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQVLGEN--NKPDMESLNNLK 370

  Fly   356 YLSCVVKESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPLV-FQPER 419
            .::.:..|.||||||:..:.|.:.|::.:.|..:|.|..:.:....:.||..::.|... |:|||
plant   371 VMTMIFNEVLRLYPPVAQLKRVVNKEMKLGELTLPAGIQIYLPTILVQRDTELWGDDAADFKPER 435

  Fly   420 HL-GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPS 476
            .. |......:..|:.||..|||.||||.||:||.|..:..:::.:..     ::.||
plant   436 FRDGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAKMAMALILQKFSF-----ELSPS 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	114/474 (24%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	120/503 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970