DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ae1 and CYP704A2

DIOPT Version :9

Sequence 1:	NP_525044.1	Gene:	Cyp4ae1 / 31193	FlyBaseID:	FBgn0015036	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_182075.1	Gene:	CYP704A2 / 819159	AraportID:	AT2G45510	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	127/474 - (26%)
Similarity:	220/474 - (46%)	Gaps:	48/474 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 FQPDNLHDKFAEYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQ-------HQLKKGTMYFAL 109
            |..|.|:|...| :.|...::.....|...::||:||:::.:|:.:       |..::.     :
plant    52 FHSDELYDYETE-IAREKPTYRFLSPGQSEILTADPRNVEHILKTRFDNYSKGHSSREN-----M 110

  Fly   110 RGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQF-VEVFDRQSSILVERLRTLSYGNEVVNIYP 173
            ...||.|:....|::|...||:.:..|...:|..| ..||.|.:|.||..:...:...:..:...
plant   111 ADLLGHGIFAVDGEKWRQQRKLSSFEFSTRVLRDFSCSVFRRNASKLVGFVSEFALSGKAFDAQD 175

  Fly   174 LVGLAALDIITETAMGVNVDAQGADS----EVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSG 234
            |:....||.|.:...||.:......|    |.:.|..:.....::||:.|      |::|.|...
plant   176 LLMRCTLDSIFKVGFGVELKCLDGFSKEGQEFMEAFDEGNVATSSRFIDP------LWKLKWFFN 234

  Fly   235 FRKQ---QAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRD 296
            ...|   :..:..:.:|...:|..:|:.||:|  |:...:...|...|:.:..|.:.:.||.:||
plant   235 IGSQSKLKKSIATIDKFVYSLITTKRKELAKE--QNTVVREDILSRFLVESEKDPENMNDKYLRD 297

  Fly   297 EVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELR----MHYGQDLFRGVILS----DFAT 353
            .:..|:..|.|||.:.:|:.||:|.::..||:|:.:|:|    .|.......|.:.|    ....
plant   298 IILNFMIAGKDTTAALLSWFLYMLCKNPLVQEKIVQEIRDVTFSHEKTTDVNGFVESINEEALDE 362

  Fly   354 LPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGY-IPVGTNVVVLLWQLLRDEAIF-TDPLVFQ 416
            :.||...:.|:||||||:|...||.|.|.|:.:|: :..|.|:..:.:.:.|...|: .|...|:
plant   363 MHYLHAALSETLRLYPPVPVDMRCAENDDVLPDGHRVSKGDNIYYIAYAMGRMTYIWGQDAEEFK 427

  Fly   417 PERHL--GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSI-- 477
            |||.|  |...|. ||:.:|.|.||||.|:|:.||..:|| :|:..:.|:....| ||....:
plant   428 PERWLKDGLFQPE-SPFKFISFHAGPRICLGKDFAYRQMK-IVSMALLHFFRFKM-ADENSKVYY 489

  Fly   478 --KIVLRSKSGVNVGLRPR 494
              .:.|....|:::...||
plant   490 KRMLTLHVDGGLHLCAIPR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	124/464 (27%)
CYP704A2	NP_182075.1	PLN03195	15..509	CDD:215627	127/474 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910