Protein Alignment Cyp4ae1 and Cyp4f16

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001343232.1
• Gene: Cyp4f16 / 70101
• MGIID: 1917351
• Length: 524
• Species: Mus musculus
• Alignment Length: 536
• Identity: 171/536 - (31%)
• Similarity: 280/536 - (52%)
• Gaps: 78/536 - (14%)

  Fly    18 LFRLALKELRHPLQGVVPSVSRVPLLG-AAWQMR-------SF-----------QPD-------- 55
            :.||::..|  .|..||.|...:.||| |:|.:.       ||           ||.
Mouse     1 MLRLSVSGL--DLGSVVTSSWHLLLLGVASWILARILAWTYSFYENCSRLSCFPQPPKKNWFSGH 63

  Fly    56 ----NLHDKFAEYVKRFGRSFMGT---VLGHVVMV--TAEPRHIDALLQGQHQLKKGTMYFA--L 109
                ..:::..:.|...|::|...   .||.|:.|  ..:|..:..|||....:....|.|.  |
Mouse    64 LGMIQSNEEGMQLVTEMGQTFQDVHLFWLGPVIPVLRIVDPAFVAPLLQAPALVAPKDMTFLRFL 128

  Fly   110 RGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTL-SYGNEVVNIYP 173
            :.||||||.||.|.:|...|:::||.|||.||:.:|::|::..:|:..:.:.| |.|:..:.::.
Mouse   129 KPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLSSEGSARLEMFE 193

  Fly   174 LVGLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATR----FMRPHLLFPHLFRLCWPSG 234
            .:.|..||.:.:...|.:.:.|.:.||.:.|:.:|::::..|    |:....|:.|.     ..|
Mouse   194 HISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSSLIIKRSLQLFLFVDFLYYHT-----ADG 253

  Fly   235 FRKQQAGVIC--LHEFTNGIIEQRRRLLAREANQDK----PTKPHAL--LDTLLRATVD-GQPLT 290
            .|.::|   |  :|.||:.:|.:||..|:.: |.|:    .||...|  :|.||.|..: |:.|:
Mouse   254 RRFRKA---CDLVHNFTDAVIRERRHTLSSQ-NHDEFLKSKTKSKTLDFIDVLLLAKDEHGKELS 314

  Fly   291 DKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRG-----VILSD 350
            |:.||.|.:||:|.|||||.||:|:.||.|:||...|::..:|:     |:|.|.     :...|
Mouse   315 DEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEV-----QELLRDREPEEIEWDD 374

  Fly   351 FATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG-YIPVGTNVVVLLWQLLRDEAIFTDPLV 414
            .|.||:|:..:||||||:.|:..:.|...:|:|:.:| .||.|...|:.::.:..:.:::.||.|
Mouse   375 LAQLPFLTMCIKESLRLHSPVIDLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEV 439

  Fly   415 FQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSIK- 478
            :.|.|...|...:.||.::|||||||||||||.||:.|||..:...:..:::||  .|.||..|
Mouse   440 YDPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRILP--DDKEPRRKP 502

  Fly   479 -IVLRSKSGVNVGLRP 493
             |:||::.|:.:.:.|
Mouse   503 EIILRAEGGLWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	163/510 (32%)
Cyp4f16	NP_001343232.1	p450	52..514	CDD:306555	156/477 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249473at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750