Protein Alignment Cyp4ae1 and Cyp4f14

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_071879.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 527
• Identity: 167/527 - (31%)
• Similarity: 275/527 - (52%)
• Gaps: 83/527 - (15%)

  Fly    32 GVVPSVS----RVPLLGAAWQM-----------RSFQPDNLHDKFAEYVKRFGRSFMGTVLGHVV 81
            |:.|.|:    .:.||||:|.:           |:::  :||. |.:..||      ..::|||.
Mouse    10 GLGPEVAFPWKTLLLLGASWILARILIQIYAAYRNYR--HLHG-FPQPPKR------NWLMGHVG 65

  Fly    82 MVTAEPRHIDAL--LQGQH---------------------------------QLKKGTMYFALRG 111
            |||...:.:..|  |.|.:                                 .||....|..|:.
Mouse    66 MVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKP 130

  Fly   112 WLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSIL-VERLRTLSYGNEVVNIYPLV 175
            |||||||:|.|.:|...|:::||.|||:||:.:|::|:..::|: .:..|.:|.|:..::::..|
Mouse   131 WLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHV 195

  Fly   176 GLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQA 240
            .|..||.:.:.....:.:.|...||.:.|:.:|:.::|.|..:| |:|..|.....|.|.|.::|
Mouse   196 SLMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQP-LMFMDLLYNLTPDGMRFRKA 259

  Fly   241 GVIC--LHEFTNGIIEQRRRLLAREANQD--KPTKPHALLD----TLLRATVDGQPLTDKQIRDE 297
               |  :||||:.:|.:|.|.|..:...|  |.......||    .||....||:.|:|:.||.|
Mouse   260 ---CNVVHEFTDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAE 321

  Fly   298 VNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRG-----VILSDFATLPYL 357
            .:||:|||||||.|.:|:.||.|:||...|::..:|:     |:|.||     :...|.|.||:|
Mouse   322 ADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEV-----QELLRGREPEEIEWDDLAQLPFL 381

  Fly   358 SCVVKESLRLYPPIPAVARCLEKDLVIDEG-YIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHL 421
            :..:||||||:||:..::||..:|:::.:| .||.|...::.::.:..:.:::.||.|:.|.|..
Mouse   382 TMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYDPFRFD 446

  Fly   422 GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSIKIVLRSKSG 486
            .|.....||.::|||||||||||||.||:.|||..:...:..::|||...:.....:::||::.|
Mouse   447 PENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELILRAEGG 511

  Fly   487 VNVGLRP 493
            :.:.:.|
Mouse   512 LWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	152/462 (33%)
Cyp4f14	NP_071879.1	CYP4F	74..515	CDD:410772	146/449 (33%)