Protein Alignment Cyp4ae1 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 146/519 - (28%)
• Similarity: 239/519 - (46%)
• Gaps: 66/519 - (12%)

  Fly     8 ALLVTRLVASLFRLALKELR--HPLQGVVPSVSRVP-LLGAAWQMRSFQPDNL--HDKFAEYVKR 67
            |||:..|:...|.|....:.  |.....:|...|.. .||.:..|.....:||  :|.|..:|::
 Frog    11 ALLLLALILICFLLFSGYIHYIHMKYDHIPGPPRDSFFLGHSPTMLRLMKNNLLMYDHFLGWVQK 75

  Fly    68 FGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMY------FALRGWLGDGLLLSRGKE-W 125
            :|.......|..|:::...|..:..||... :..|...|      |.:| ::|.||:..|..: |
 Frog    76 YGPVVRINGLHRVIILVVSPEAVKELLMSP-KYSKDKFYDVIANMFGVR-FMGKGLVTDRDYDHW 138

  Fly   126 HTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGV 190
            |..|:|:.|.|..:.|...:..|:.::..|:|:|...:.|...:.::.::....||:|.:.|.|:
 Frog   139 HKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLTLDVIGKVAFGM 203

  Fly   191 NVDAQGAD--------SEVVHAVKDLTN-----ILATRFMRPHLLFPHLFRLCWPSGF-RKQQAG 241
            .:::...|        |.|:..:.::.|     .||.|                  || ||.|..
 Frog   204 ELNSLNDDLTPFPKAISLVMKGIVEMRNPMVRYSLAKR------------------GFIRKVQES 250

  Fly   242 VICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGH 306
            :..|.:.....||:|::.:     ||....|..:|..:|:.....:....:.:.|...||...|.
 Frog   251 IRLLRQTGKECIERRQKQI-----QDGEEIPVDILTQILKGAAMEEECDPEILLDNFVTFFIAGQ 310

  Fly   307 DTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPI 371
            :||.:.:||.:..|.|:..:.:|...|:....|..  |.:...|...|.|||.|:||:|||||..
 Frog   311 ETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSK--RDIEYEDLGKLQYLSQVLKETLRLYPTA 373

  Fly   372 PAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSP-YSYIP 435
            |..:|.|.:|:|||...:|....:::..:.:.|.|..::|||.|.|:| ...:||:  | |||.|
 Frog   374 PGTSRGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDR-FSPDAPK--PYYSYFP 435

  Fly   436 FSAGPRNCIGQKFALLEMKTMVTKVIRHYQL-LPMGADVEPSIKIV----LRSKSGVNVGLRPR 494
            ||.|||:||||.|:.:|.|.::.|:::.|:. |..|    .|.||:    ||...||...||||
 Frog   436 FSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFELAEG----QSFKILDTGTLRPLDGVICRLRPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	133/480 (28%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	135/484 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920