Protein Alignment Cyp4ae1 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 511
• Identity: 122/511 - (23%)
• Similarity: 227/511 - (44%)
• Gaps: 56/511 - (10%)

  Fly     2 LVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVK 66
            ||||::.|        ||...:...|..::..:|.....|.:|.   :.|: ...|.:...|..|
Zfish    13 LVVLVITL--------LFIYGVWPHRFFIKLGIPGPRPWPFVGT---LLSY-AKGLCNFDMECAK 65

  Fly    67 RFGRSFMGTVLGHV-VMVTAEPRHIDALLQGQ------HQLKKGTMYFALRGWLGDGLLLSRGKE 124
            ::|:.: |...|.: :::.|:...|..:|..:      ::.|:.|   .|.|...||:::.:.:.
Zfish    66 KYGKVW-GIYDGRLPILMVADLEVIKVVLVKECYSNFINRRKRTT---GLAGPFSDGIIMVKDER 126

  Fly   125 WHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMG 189
            |..||..::|.|....|::...:....:...::.::... ..:.|.|..:|...:||:||.::..
Zfish   127 WKRMRSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKKD-PEQPVKIKEVVAPYSLDVITSSSFS 190

  Fly   190 VNVDA--QGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEFTNGI 252
            |::|:  ...|..|::..|.:...:....:...||||.|       ....::.||....:.....
Zfish   191 VDIDSINNPEDPFVINVKKFIQFNMFNPLLLLILLFPSL-------AIPLKKMGVTLFSKSAMDF 248

  Fly   253 IEQRRRLLAREANQDKPTKPHALL---------DTLLRATVDGQP---LTDKQIRDEVNTFIFEG 305
            .....:.:..:.|::...:...|.         |.:..:....||   |||.:|..:...||..|
Zfish   249 FYSVLKKIKDDHNKESEGRVDFLKLMLQNQIPDDQIQDSDTSEQPAKGLTDHEILSQSLVFILGG 313

  Fly   306 HDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPP 370
            ::||::.::|.||.|:.:....:||.||:..::..|  ..:.......:.||...:.||:||.|.
Zfish   314 YETTSTTLTFLLYNLATNPDCLEKLVEEIDKNFPLD--TPITYDALMRMDYLEMAINESMRLLPT 376

  Fly   371 IPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIP 435
            .|.:.|..:|.:||:...||.||.|.:..:.|..|..|:..|..|:|||...|.......|::||
Zfish   377 APRLERSAKKTVVINGLTIPEGTLVGIPTYVLSHDPDIWESPGEFRPERFSPENKSEFLQYAFIP 441

  Fly   436 FSAGPRNCIGQKFALLEMKTMVTKVIRHYQL---------LPMGADVEPSIKIVLR 482
            |..|||||||.::|::.||..|.|:::::.:         |.|....:|.:.|.|:
Zfish   442 FGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIPLEMNVTFQPKVPITLK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	105/437 (24%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	106/444 (24%)