Protein Alignment Cyp4ae1 and Cyp6a22

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 123/535 - (22%)
• Similarity: 223/535 - (41%)
• Gaps: 112/535 - (20%)

  Fly     6 LVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDN--------LHDKFA 62
            :||||:..|....:.:..:......:|:....:|.|:    ..|..|:.:.        :::||
  Fly     4 VVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPV----GNMEGFRKNKHFIDIVTPIYEKF- 63

  Fly    63 EYVKRFGRSFMG--TVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALR-GWLGDGLLLSRGKE 124
               |..|..|.|  .:|..||:||........|:|.....:...||...| ..|...|....|.:
  Fly    64 ---KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPK 125

  Fly   125 WHTMRKIITPTFHFSILEQF----VEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITE 185
            |..:|:.::|||..:.::..    .||.:..:.:..|.......|  ::.|..|:.....|:|..
  Fly   126 WRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG--ILEIGDLMARYTSDVIGR 188

  Fly   186 TAMGV------NVDAQ------GADSEVVHA------VKDLTNILATRFMRPHLLFPHLFRLCWP 232
            .|.||      |.:|:      .|.||..|.      ::....:  .||:|...:...:
  Fly   189 CAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEV--ARFLRMRQIHQDI------ 245

  Fly   233 SGF----------RKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQ 287
            :.|          ::::.|:: ..:|.|.:||.::|                           |:
  Fly   246 TDFYVGIVRETVKQREEQGIV-RSDFMNLLIEMKQR---------------------------GE 282

  Fly   288 PLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEE----LRMHYGQDLFRGVIL 348
             ||.:::..:...|...|.||:.|.:.|.||.|::..|:|.||.||    ||:|.|:..:
  Fly   283 -LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTY----- 341

  Fly   349 SDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG----YIPVGTNVVVLLWQLLRDEAIF 409
            .....|.|:..|:.|:||.||.:|.:.| :.:.|...:|    ||..|..:::.::.:..|.|::
  Fly   342 DSMQELRYMELVIAETLRKYPILPQLTR-ISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALY 405

  Fly   410 TDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIR--HYQLLPMGAD 472
            .:|..|.|||.|.::..:....:::||..|||||||.:|..::....:..::|  |:.:.|.
  Fly   406 PEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPR--- 467

  Fly   473 VEPSIKIVLRSKSGV 487
            .:|.|:.:   ||.:
  Fly   468 TDPKIEFL---KSNI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	107/455 (24%)
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	110/465 (24%)