Protein Alignment Cyp4ae1 and Cyp6a2

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 133/551 - (24%)
• Similarity: 232/551 - (42%)
• Gaps: 116/551 - (21%)

  Fly     1 MLVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDN-LHDKFAEY 64
            |.|::.:.:.::.|:|.|:.   :...:..:..||..:..||.|   .|..|:.:. :||.|.:|
  Fly     1 MFVLIYLLIAISSLLAYLYH---RNFNYWNRRGVPHDAPHPLYG---NMVGFRKNRVMHDFFYDY 59

  Fly    65 VKRFGRS---FMGTVLGHVVMVTAEPRH--IDALLQGQHQLKKGTMYFALRGWLGDG-------- 116
            ..::.:|   |:|....|      :|..  :|..| .::.|.|....||.||...:|
  Fly    60 YNKYRKSGFPFVGFYFLH------KPAAFIVDTQL-AKNILIKDFSNFADRGQFHNGRDDPLTQH 117

  Fly   117 LLLSRGKEWHTMRKIITPTFH-----------FSILEQFVEVFDRQSSILVERLRTLSYGNEVVN 170
            |....||:|..||:.:||||.           ..:.|:||:|       :.|::.....| .|:.
  Fly   118 LFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKV-------ITEQVPAAQNG-AVLE 174

  Fly   171 IYPLVGLAALDIITETAMGVNVD------------AQGADSEVVHAVKDLTNI------LATRF- 216
            |..|:.....|:|...|.|:..:            .|...:::.|. |.||..      ||:|.
  Fly   175 IKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHG-KLLTMFVFSFPKLASRLR 238

  Fly   217 --MRP---HLLFPHL----FRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKP 272
              |.|   |..|..|    ..|.....|::        ::|.|.:||.::             |.
  Fly   239 MRMMPEDVHQFFMRLVNDTIALRERENFKR--------NDFMNLLIELKQ-------------KG 282

  Fly   273 HALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEE---- 333
            ...||.  ...::|..:  .::..:|..|...|.:|::|.:|:|||.|::::.:|.:|..|
  Fly   283 RVTLDN--GEVIEGMDI--GELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTV 343

  Fly   334 LRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVI---DEGYIPVGTNV 395
            |....||..:..:     ..:.||:.|:.|:||||..:|.:.|....|.|:   ::..|..||.|
  Fly   344 LEEQEGQLTYESI-----KAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQV 403

  Fly   396 VVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKV 460
            ::......|||.::.:|..|.|||...|:........::||..|||||||.:|..::.:..:.::
  Fly   404 IIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQI 468

  Fly   461 IRHYQLLPMGADVEP----SIKIVLRSKSGV 487
            |..:::........|    .:.|||.:..|:
  Fly   469 ISRFRVSVCDTTEIPLKYSPMSIVLGTVGGI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	114/472 (24%)
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	116/477 (24%)