Protein Alignment Cyp4ae1 and Cyp4v3

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 189/487 - (38%)
• Similarity: 278/487 - (57%)
• Gaps: 42/487 - (8%)

  Fly    34 VPSVSRV-PLLGAAWQMRSFQPDN--LHDKFAEYVKRFGR-SFMGTVLGHVVMVTA-EPRHIDAL 93
            :|||:|. ||:|.|..|:   |:|  ...:..:|.:.|.. ..:...:|.|.:|.. :..:::.:
  Rat    50 IPSVARAYPLVGHALFMK---PNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVI 111

  Fly    94 LQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVER 158
            |....|:.|..||..|:.|||.|||.|.|.:|...||::||:|||:|||.|::|.:.|::|||.:
  Rat   112 LTSSKQIDKSFMYKFLQPWLGLGLLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNK 176

  Fly   159 LRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQ-GADSEVVHAVKDLTNILATRFMRPHLL 222
            |.. ....|..|.:..:.|.|||||.|||||.|:.|| ..|||.|..|..:::::..|...|...
  Rat   177 LEK-HVNQEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFW 240

  Fly   223 FPHLFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQD----------KPTKPHALLD 277
            | .|:.|.:..| |..:.|:..||.|||.:|.:  |:.||:|.||          ..||..|.||
  Rat   241 F-DLWYLMFKEG-RDHKKGLKSLHTFTNNVIAE--RVNARKAEQDCIGAGRGPLPSKTKRKAFLD 301

  Fly   278 TLLRAT-VDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQD 341
            .||..| .:|..|:.:.||:||:||:|||||||.:|:::.||||..:..||:|:.:||...:|:.
  Rat   302 LLLSVTDEEGNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRS 366

  Fly   342 LFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGY-IPVGTNVVVLLWQLLRD 405
             .|.|.|.|...|.||.||:||:||::|.:|..||.|.:|..: .|| |..||..|::.:.|.||
  Rat   367 -HRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEV-AGYKISKGTEAVIIPYALHRD 429

  Fly   406 EAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQL---- 466
            ...|.||..|||||...|.:....||:|:|||||||||||||||::|.||::..::|.:.:
  Rat   430 PRYFPDPEEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIESNQ 494

  Fly   467 ----LPMGADVEPSIKIVLRSKSGVNVGLRPR 494
                |.:..|      ::||..:|:.:.|:.|
  Rat   495 KREELGLAGD------LILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	186/476 (39%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	176/451 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249473at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850