Protein Alignment Cyp4ae1 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 140/480 - (29%)
• Similarity: 234/480 - (48%)
• Gaps: 63/480 - (13%)

  Fly    31 QGVVPSVSRVP------LLGAAWQMRSFQPDNLHDKFAEYVKRFGRSFMGTVLGHVVMVTAEPRH 89
            |.::..|...|      |.|:..:::.:.||        |:|
  Rat    71 QDILTRVKNFPSACPQWLWGSNVRIQVYDPD--------YMK----------------------- 104

  Fly    90 IDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSI 154
               |:.|:...|....|..|..|:|.||||..|:.|...|:::||.||:..|:.:|.:......|
  Rat   105 ---LILGRSDPKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSVRI 166

  Fly   155 LVERLRTLSYGNEVVNIYPLVGLAALDIITETAM----GVNVDAQGADSEVVHAVKDLTNILATR 215
            ::::...:...:..:.|:..:.|..||.|.:.|.    .|.:|.:  ....:.||:||.|:   .
  Rat   167 MLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQEGSVQLDRK--YKSYIKAVEDLNNL---S 226

  Fly   216 FMRPHLLFPH---LFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHAL-- 275
            |.|...:|..   ::.|  .|..||.::.....||.|:.:|:.|:..|..|....|..:...|
  Rat   227 FFRIRNIFHQNDIIYSL--SSNGRKARSAWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDF 289

  Fly   276 LDTLLRATVD-GQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYG 339
            ||.||.|.:: |..|:||.:|.||:||:|||||||.|.:|:..|.|:.:...||...:|::...|
  Rat   290 LDILLFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLG 354

  Fly   340 QDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG-YIPVGTNVVVLLWQLL 403
            ..  ..:...|...:||.:..:||:||:|||:.||:|.|...:...:| .:|.|..|::..:.|.
  Rat   355 DG--ASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLH 417

  Fly   404 RDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLP 468
            .:..::.:|.||.|.| ...|:.|.| :|::|||.|.|||||::||:.|:|..|...:..::|||
  Rat   418 HNPTVWPNPEVFDPYR-FAPESSRHS-HSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP 480

  Fly   469 MGADVE-PSIKIVLRSKSGVNVGLR 492
            ....:. |..::||:||:|:.:.|:
  Rat   481 DPTRIPIPIPRLVLKSKNGIYLRLK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	130/424 (31%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	139/476 (29%)