Protein Alignment Cyp4ae1 and Cyp19a1

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_058781.2
• Gene: Cyp19a1 / 25147
• RGDID: 2457
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 447
• Identity: 93/447 - (20%)
• Similarity: 182/447 - (40%)
• Gaps: 79/447 - (17%)

  Fly    60 KFAEYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKE 124
            |.:.|:.|||                ..|.:..:  |.|:               :|::.:....
  Rat   108 KHSNYISRFG----------------SKRGLQCI--GMHE---------------NGIIFNNNPS 139

  Fly   125 -WHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAM 188
             |.|:|...........|.:.|||........::||..::..:..|::..|:....||......:
  Rat   140 LWRTVRPFFMKALTGPGLIRMVEVCVESIKQHLDRLGDVTDNSGYVDVVTLMRHIMLDTSNTLFL 204

  Fly   189 GVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEFTNGII 253
            |:.:|    :|.:|..::...|......::|::    .|::.|.  :||.:..|..|.:....::
  Rat   205 GIPLD----ESSIVKKIQGYFNAWQALLIKPNI----FFKISWL--YRKYERSVKDLKDEIEILV 259

  Fly   254 EQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLY 318
            |::|:   :.::.:|..........|:.|...|. ||.:.:...:...:....||.:..:...|.
  Rat   260 EKKRQ---KVSSAEKLEDCMDFATDLIFAERRGD-LTKENVNQCILEMLIAAPDTMSVTLYVMLL 320

  Fly   319 LLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLV 383
            |::.:..|:..:.:|:....|.   |.:.:.|...|..:...:.||||..|.:..|.|...:|.|
  Rat   321 LIAEYPEVETAILKEIHTVVGD---RDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDV 382

  Fly   384 IDEGYIPV--GTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYI-PFSAGPRNCIG 445
            || || ||  |||:::.:.::.|.| .|..|..|..|..     .:..||.|. ||..|||:|.|
  Rat   383 ID-GY-PVKKGTNIILNIGRMHRLE-YFPKPNEFTLENF-----EKNVPYRYFQPFGFGPRSCAG 439

  Fly   446 QKFALLEMKTMVTKVIRHYQL----------LPMGADV-------EPSIKIVLRSKS 485
            :..|::.||.::..:::.:.:          :|...|:       .|.::|:...::
  Rat   440 KYIAMVMMKVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHLDEDSPIVEIIFSPRN 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	93/447 (21%)
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	91/434 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030