Protein Alignment Cyp4ae1 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 165/514 - (32%)
• Similarity: 267/514 - (51%)
• Gaps: 50/514 - (9%)

  Fly     2 LVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVP---LLGAAWQMRSFQPDNLHDKFAE 63
            :|:|:|      :|..||.|.|:  |..|...:.|....|   |.|.|.:::..   ...||...
  Rat    19 VVILMV------IVLKLFSLLLR--RQKLARAMDSFPGPPTHWLFGHALEIQKL---GSLDKVVS 72

  Fly    64 YVKRFGRS---FMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEW 125
            :.::|..:   :.|..:|.:.:.  ||.:..| :..:...|...:|.....|:|.|||:..|.:|
  Rat    73 WAQQFPHAHPLWFGQFVGFLNIY--EPDYAKA-VYSRGDPKAADVYDFFLQWIGKGLLVLDGPKW 134

  Fly   126 HTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGV 190
            ...||::||.||:.:|:.:|.:|...:.:::::....:..|:..:|:..||..|||.:.:...|.
  Rat   135 FQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGK 199

  Fly   191 NVDAQG-ADSEVVHAVKDLTNILATRF--MRPHLLFPHLFRLCW--PSGFRKQQAGVICLHEFTN 250
            .....| .|:....||.|||.::..|.  .:.|..|     :.|  |.|.|..:|..|. |:.|:
  Rat   200 GDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDF-----IYWLTPHGRRFLRACKIA-HDHTD 258

  Fly   251 GIIEQRRRLLAREANQDKPTKPHAL--LDTLLRATVD-GQPLTDKQIRDEVNTFIFEGHDTTTSA 312
            .:|.||:..|..|..:.|..:...|  ||.||....: |..|:|.::|.||:||:|||||||||.
  Rat   259 EVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDTFMFEGHDTTTSG 323

  Fly   313 VSFCLYLLSRHEAVQQKLFEELRMHYG-QDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVAR 376
            :|:.||.::.:...||...||:|...| ||.|:   ..|.|.:.||:..:||..|||||:|.|.|
  Rat   324 ISWFLYCMALYPEHQQLCREEVRGILGDQDSFQ---WDDLAKMTYLTMCMKECFRLYPPVPQVYR 385

  Fly   377 CLEKDLV-IDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGP 440
            .|.|.:. :|...:|.|:.:.:.::.|.|:..::.||.||.|.|...|.|....|::::||||||
  Rat   386 QLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFAFMPFSAGP 450

  Fly   441 RNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPS---IKI---VLRSKSGVNVGLRP 493
            ||||||:||:.|||.:....:..::.     .::||   ||:   :||||:|:::.|:|
  Rat   451 RNCIGQQFAMNEMKVVTALCLLRFEF-----SLDPSKMPIKVPQLILRSKNGIHLYLKP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	144/428 (34%)
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	148/450 (33%)