Protein Alignment Cyp4ae1 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 132/553 - (23%)
• Similarity: 225/553 - (40%)
• Gaps: 105/553 - (18%)

  Fly     2 LVVLLVALLVTRLVASLFR-LALKELRHPLQGVVPSVSRVPLLGAAWQM------RSFQPDNLHD 59
            ::|.|||::  .:||..|: :.....|..::|.|    .:|.:|:.:.:      |.|
 Worm     3 VIVCLVAII--GVVAGYFKWIHSYWKRRGIEGPV----GLPFIGSFYDLADREKPRGF------- 54

  Fly    60 KFAEYVKRFGRSFMGTVLGHV-VMVTAEPRHIDALLQGQHQLKKGTMYFA------LRGWL---- 113
            ...::.|.||:.| |...|.: |:|.::   :| :|| :..:||...::|      :.|.|
 Worm    55 IINKWTKMFGKVF-GYYEGVIPVLVVSD---LD-MLQ-EMFIKKFDCFYARKTTNLIHGNLECSQ 113

  Fly   114 ---GDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLV 175
               ...|..:||..|..:|.:.:|.|....|:|..|..:.....:|:.: :.....|..||:...
 Worm   114 EEPRVNLFAARGARWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHM-SKQVNGEAFNIHEYY 177

  Fly   176 GLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQA 240
            .....|:|:..|||.....| .::|.|..||.:       |:|.:.::|....:.:| ||.....
 Worm   178 QEFTYDVISRLAMGQTYSEQ-FNNEGVDIVKKI-------FLRKNRVYPWYLAVMFP-GFENTIK 233

  Fly   241 GVICLHEFTNG------------IIEQRRRLLAREANQDKPTKPHALLDTLLRATVD-------- 285
            .....||...|            .:..|.:..|....|......:..:|..|....|
 Worm   234 NTFFNHEAVRGGDVGKLLKFCETAVHDRLKERADNVEQGIENPHNDFIDMFLDYYTDTNIEDNAF 298

  Fly   286 ----GQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEEL-----RMHYGQD 341
                .:.:|.:.:......|:..|.|||.:.:::..|||::|....:|:.:|:     ..|...|
 Worm   299 GIKVEKKVTSEDVIGACFVFLLAGFDTTANTLAYASYLLAKHPQEMRKVQDEIDRICTSEHISYD 363

  Fly   342 LFRGVILSDFATLPYLSCVVKESLRLYPPIPAVA------RCLEKDLVIDEGYIPVGTNVVVLLW 400
                    |...|.|:..|::|:||:||    ||      .|::. ..:...||..|..:...:.
 Worm   364 --------DIGKLRYMDAVIREALRMYP----VAWFACSRECVQA-TTLGNYYIEKGVRIEADVR 415

  Fly   401 QLLRDEAIF-TDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHY 464
            .|...|.|: .:...|.|||.| |.:||.: .|:|||.||||.|:|.:..|.|.||.:..::|.:
 Worm   416 ALHYSEEIWGKNANEFVPERWL-ESSPRHN-MSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRF 478

  Fly   465 QLLPMGADVEPSIKI---VLRSKSGVNVGLRPR 494
            .:| .|...|..:.:   ...|...|.|.|..|
 Worm   479 SIL-AGPKTEKELHLQGCTTTSPEKVTVHLMTR 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	110/465 (24%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	114/474 (24%)