Protein Alignment Cyp4ae1 and cyp-13A10

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_496085.3
• Gene: cyp-13A10 / 174522
• WormBaseID: WBGene00014254
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 120/515 - (23%)
• Similarity: 209/515 - (40%)
• Gaps: 106/515 - (20%)

  Fly    34 VPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVK-RFGRSFMGTVLGHV--VMVTAEPRHIDAL-- 93
            :|.....||:|      || |..|..::.:|:: |......|.:.|:.  .:.|.....||.:
 Worm    31 IPGPLGYPLVG------SF-PKTLKSEYPQYLQIRDWTKLYGPIYGYTEGTIKTLIVSDIDIVRQ 88

  Fly    94 ----------------LQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILE 142
                            :||..:..:.|..|:.:|:           .|..:|.|.:|||..:.|.
 Worm    89 IFVEQYDNFYGRKLNPIQGDPEKDERTNLFSAQGF-----------RWKRLRAISSPTFSNNSLR 142

  Fly   143 QFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEVVHAVKD 207
            :.....:..:..|:..:...:...:.:::........:|.|...||| ..|:|...:.::..|:.
 Worm   143 KINVTVEDSAMELLRHIEEQTSEGQQIDMLQFYQEFTMDTIGRIAMG-QTDSQMFKNPLLKFVRA 206

  Fly   208 L--TNILATRFMRPHL-----LFPHL------FRLCWP----SGFRKQQAGVICLHEFTNGIIEQ 255
            :  .|       |.|:     :||.|      |.|.:|    :.|         :|.....:...
 Worm   207 IFGDN-------RKHIPLIGGVFPTLAQVFRFFMLKFPLLGAANF---------IHVNKTVVTAV 255

  Fly   256 RRRLLARE---ANQDKPTKPHALLDTLLRATVD-------------------GQPLTDKQIRDEV 298
            :.|:..||   .|..:..:|...:|..|.|..|                   .:.||.::|..:.
 Worm   256 QNRIDQRENDRKNGIEIGEPQDFIDLFLEARADDVEHFQENNGDFSKTSSYGNRQLTTQEIVGQC 320

  Fly   299 NTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKE 363
            ..|:..|.|||..::|:..:||:.|..||:||.||:..   :.:...:.....:.|.|:.|::||
 Worm   321 LVFLIAGFDTTALSLSYTTFLLATHPEVQKKLQEEIER---ECIEPSISFDHLSKLKYMDCIIKE 382

  Fly   364 SLRLYPPIPAVA---RCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHLGEE 424
            :|||| |:..:|   ||: :...:....:.|||.|.|..|.|..|..|: .|...|:|||.|...
 Worm   383 TLRLY-PLGTMANSRRCM-RATKLGNVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPN 445

  Fly   425 APRL-SPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSIKIVLRS 483
            ..:: ....||.|..|||.|:|.:.|.:|.|.::..::|.| ...:|...|..:|:|.|:
 Worm   446 CDQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKY-TFEVGTKTEIPLKLVGRA 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	109/472 (23%)
cyp-13A10	NP_496085.3	CYP3A-like	64..509	CDD:410678	110/475 (23%)