Protein Alignment Cyp4ae1 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 119/405 - (29%)
• Similarity: 194/405 - (47%)
• Gaps: 59/405 - (14%)

  Fly   107 FALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNI 171
            |...|.|...:.||..:||..:|.:::|||....|::...:.::.:.:||:.::..:.....:.:
  Rat   108 FGPAGILKKAITLSEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITM 172

  Fly   172 YPLVGLAALDIITETAMGVNVDA-QGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWP--- 232
            ..:.|..::|:||.|:.|||||: ....:..|..||.|   |...|:.|..|...||....|
  Rat   173 KDIFGAYSMDVITGTSFGVNVDSLNNPQNPFVQKVKKL---LKFNFLDPFFLSVILFPFLTPVFE 234

  Fly   233 ----SGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDG-----QP 288
                :.|.|.      :.:|....:|:    :.....|:|..:....|..::.:...|     |.
  Rat   235 AFDITVFPKD------VMKFFRTSVER----MKENRMQEKVKQRLDFLQLMINSQSSGDKESHQG 289

  Fly   289 LTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFAT 353
            |||.:|..:...|||.|::||:||:||.||||:.|..:|:||.:|:.                |.
  Rat   290 LTDVEIVAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEID----------------AA 338

  Fly   354 LP--------------YLSCVVKESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLR 404
            ||              ||..|:.|:|||:|....:.|..:||:.|:..:||.||.|:|..:.|.:
  Rat   339 LPNKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEINGVFIPKGTVVMVPTFALHK 403

  Fly   405 DEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPM 469
            |...:.:|..|.|||...:....::||.|:||..|||||||.:|||:.||..:.:|::::.   .
  Rat   404 DPKCWPEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFS---F 465

  Fly   470 GADVEPSIKIVLRSK 484
            |...|..|.:.||.|
  Rat   466 GLCKETQIPLKLRKK 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	119/405 (29%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	119/405 (29%)