Protein Alignment Cyp4ae1 and Cyp4b1

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 520
• Identity: 169/520 - (32%)
• Similarity: 271/520 - (52%)
• Gaps: 62/520 - (11%)

  Fly     2 LVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVP---LLGAAWQMRSFQPDNLHDKFAE 63
            :|:|:|.:|  :|::.|||      |..|...:.|....|   |.|.|.::   |.....||...
Mouse    19 VVILMVTVL--KLLSLLFR------RQKLARALDSFPGPPKHWLFGHALEI---QKTGGLDKVVT 72

  Fly    64 YVKRFGRS---FMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEW 125
            :.::|..:   ::|..:  |.:...||.:..| :..:...|...:|.....|:|.|||:..|.:|
Mouse    73 WTEQFPYAHPLWLGQFI--VFLNIYEPDYAKA-VYSRGDPKAAYVYDFFLQWIGKGLLVLEGPKW 134

  Fly   126 HTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGV 190
            ...||::||.||:.:|:.:|.:|...:.:::::....:..|:..:|:..||..|||.:.:...|
Mouse   135 FQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFG- 198

  Fly   191 NVDAQGADSEVVH-------AVKDLTNILATRF--MRPHLLFPHLFRLCW--PSGFRKQQAGVIC 244
                 ..||.:.|       ||.|||.::..|.  .:.|..|     :.|  |.|.|..:|..|.
Mouse   199 -----KGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDF-----IYWLTPHGRRFLRACQIA 253

  Fly   245 LHEFTNGIIEQRRRLLAREANQDKPTKPHAL--LDTLLRATVD-GQPLTDKQIRDEVNTFIFEGH 306
             |:.|:.:|.||:..|..|..|.|..:...|  ||.||.|..: |..|:|..:|.||:||:||||
Mouse   254 -HDHTDHVIRQRKAALQDEKEQKKLQERRHLDFLDILLGARDESGIKLSDADLRAEVDTFMFEGH 317

  Fly   307 DTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYG-QDLFRGVILSDFATLPYLSCVVKESLRLYPP 370
            |||||.:|:.||.::.:...||:..||:|...| :|.|:   ..|.|.:.||:..:||..|||||
Mouse   318 DTTTSGISWFLYCMALYPMHQQRCREEVREILGDRDSFQ---WDDLAQMTYLTMCMKECFRLYPP 379

  Fly   371 IPAVARCLEKDLV-IDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYI 434
            :|.|.|.|.|.:. :|...:|.|:.:.:.::.|.|:.|::.||.||.|.|...|......|::::
Mouse   380 VPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFM 444

  Fly   435 PFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPS---IKI---VLRSKSGVNVGLRP 493
            ||||||||||||:||:.|||.:....:..::..|     :||   ||:   :||||:|:::.|:|
Mouse   445 PFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSP-----DPSKIPIKVPQLILRSKNGIHLYLKP 504

  Fly   494  493
            Mouse   505  504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	156/478 (33%)
Cyp4b1	NP_031849.1	p450	47..500	CDD:278495	156/478 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845248
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740