Protein Alignment Cyp4ae1 and Cyp19a1

DIOPT Version :9

• Sequence 1: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001335100.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 485
• Identity: 107/485 - (22%)
• Similarity: 200/485 - (41%)
• Gaps: 71/485 - (14%)

  Fly    25 ELRHPLQG----VVP---SVSRVPLL---G---AAWQMRS------------FQPDNLHDKFA-- 62
            |:.:|:|.    :||   :||.:|||   |   ..|...|            ..|...|.:|.
Mouse     4 EMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSSSIPGPGYCLGIGPLISHGRFLWM 68

  Fly    63 -------EYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQL-----KKGTMYFALRGWLGD 115
                   .|.|.:|......:.|...::.::...:..:::..|.:     |:|....   |...:
Mouse    69 GIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHYISRFGSKRGLQCI---GMHEN 130

  Fly   116 GLLLSRGKE-WHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAA 179
            |::.:.... |.|:|...........|.:.|||........::||..::..:..|::..|:....
Mouse   131 GIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTDTSGYVDVLTLMRHIM 195

  Fly   180 LDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVIC 244
            ||......:|:.:|    :|.:|..::...|......::|::    .|::.|.  :||.:..|..
Mouse   196 LDTSNMLFLGIPLD----ESAIVKKIQGYFNAWQALLIKPNI----FFKISWL--YRKYERSVKD 250

  Fly   245 LHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTT 309
            |.:....::|::|.   :.:..:|..........|:.|...|. ||.:.:...:...:....||.
Mouse   251 LKDEIAVLVEKKRH---KVSTAEKLEDCMDFATDLIFAERRGD-LTKENVNQCILEMLIAAPDTM 311

  Fly   310 TSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAV 374
            :..:.|.|.|::.:..|:..:.:|:....|.   |.:.:.|...|..:...:.||:|..|.:..|
Mouse   312 SVTLYFMLLLVAEYPEVEAAILKEIHTVVGD---RDIKIEDIQNLKVVENFINESMRYQPVVDLV 373

  Fly   375 ARCLEKDLVIDEGYIPV--GTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYI-PF 436
            .|...:|.||| || ||  |||:::.:.::.|.| .|..|..|..|..     .:..||.|. ||
Mouse   374 MRRALEDDVID-GY-PVKKGTNIILNIGRMHRLE-YFPKPNEFTLENF-----EKNVPYRYFQPF 430

  Fly   437 SAGPRNCIGQKFALLEMKTMVTKVIRHYQL 466
            ..|||.|.|:..|::.||.::..::|.:|:
Mouse   431 GFGPRGCAGKYIAMVMMKVVLVTLLRRFQV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ae1	NP_525044.1	p450	35..486	CDD:278495	103/471 (22%)
Cyp19a1	NP_001335100.1	p450	48..488	CDD:306555	94/441 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030