Protein Alignment Cyp4d2 and ERG5

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 118/513 - (23%)
• Similarity: 208/513 - (40%)
• Gaps: 113/513 - (22%)

  Fly    10 LVAFAT----LLLWDFLWRRRGNGILPGPR----PL--PFLGNLLMYRGLDPEQIMDFVKKNQRK 64
            |..|||    ||:||.:..:...|.:.||:    |:  |||      ..|||:     .::.:.|
Yeast    46 LKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFL------ESLDPK-----FEEYKAK 99

  Fly    65 Y--GRLYRVWILHQLAVFSTDPRDI-EFVLSSQQHI---TKNNLYKLLN-C-WLGDGLLMSTGRK 121
            :  |.|..|.|.|:..|.:: .||: ..:|.|.:.:   ..:...|:|. | |     :...|:.
Yeast   100 WASGPLSCVSIFHKFVVIAS-TRDLARKILQSSKFVKPCVVDVAVKILRPCNW-----VFLDGKA 158

  Fly   122 WHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQ-----SRADGMTPINIF----PVICLTAL 177
            ....||.:...|..:.|.|::...:|   :|.:.:.     |:.:...|...|    .::|..:|
Yeast   159 HTDYRKSLNGLFTKQALAQYLPSLEQ---IMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSL 220

  Fly   178 DIIAETAMGTKINAQKNPNLPY-VQAVNDVTNI-LIKRFIHAWQRVDWIFRLTQPTEAKRQDKAI 240
            :......: |:...:|..:..| |.|..::.|. :|..:...|.            ..|..|.|:
Yeast   221 NSFCGNYI-TEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWY------------GKKTADMAM 272

  Fly   241 KVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDED----- 300
            |:.    ||..:..::.:....|.               :.::|...:...|....:|:|
Yeast   273 KIF----ENCAQMAKDHIAAGGKP---------------VCVMDAWCKLMHDAKNSNDDDSRIYH 318

  Fly   301 -------IREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDL 358
                   |.|.|.||:|...|.::|...:....::..|:|..::::|...|...|..:.:.|..:
Yeast   319 REFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLI 383

  Fly   359 GELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTM--------GIFVLLRDPEY 415
            .::|:...||||:||..|||.|:       ..:..|:.|...|:|.        .::..|.|||.
Yeast   384 EKMKYTNMVIKETLRYRPPVLMV-------PYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEV 441

  Fly   416 FESPDEFRPERF-DADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
            :|:||||.|||: :..........::.|..||..|:||.:.|:    |.:.||..|.|
Yeast   442 YENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMI----TFAALLGKFAL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	109/487 (22%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	99/445 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I1557
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I1313
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
TreeFam	0	0.000	Not matched by this tool.
	4	3.960