DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d2 and CYP702A1

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_176744.1	Gene:	CYP702A1 / 842878	AraportID:	AT1G65670	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	120/519 - (23%)
Similarity:	208/519 - (40%)	Gaps:	101/519 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLLVAFATLLLWDFLW------RRRGNGILPGPRPLPFLGNLLMY-RGLDPEQIMDFVKKNQRKY 65
            ||.|..:.:::..|.|      .:....:.||....|.:|....: :..|..|...|:|:...:|
plant     7 LLTVMVSLIVVKLFHWIYQSKNPKPNEKLPPGSMGFPIIGETFEFMKPHDAFQFPTFIKERIIRY 71

  Fly    66 GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNN----LYKLLNCWLGDGLLMSTGRKWHGRR 126
            |.::|..:.....:.|||       :.....|.|.|    |.|.:....|:..|....::.|...
plant    72 GPIFRTSLFGAKVIISTD-------IELNMEIAKTNHAPGLTKSIAQLFGENNLFFQSKESHKHV 129

  Fly   127 KIITPTFHFKILE------QFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDI---IAE 182
            :.:|    |::|.      ..::..|..:...:|:...|.            ||...:|   |..
plant   130 RNLT----FQLLGSQGLKLSVMQDIDLLTRTHMEEGARRG------------CLDVKEISSKILI 178

  Fly   183 TAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQP-TEAKRQDKAIK-VMHD 245
            ..:..|:.....|     :|..::. :..:.|...|.|    |.|..| |...:..||.| ::|.
plant   179 ECLAKKVTGDMEP-----EAAKELA-LCWRCFPSGWFR----FPLNLPGTGVYKMMKARKRMLHL 233

  Fly   246 FTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGA-PLSDEDIREEVDTFM 309
            ..|.|:::|          .:.||    ||:         ..:...:|| .:|.::..|.:.|..
plant   234 LKETILKKR----------ASGEE----LGE---------FFKIIFEGAETMSVDNAIEYIYTLF 275

  Fly   310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVL-GE-DRKSPVTLRDLGELKFMENVIKESL 372
            ...::||...::..:..||.:|:|.:.|.:|...:: |: ::::.:|..:...:.|.:.||.|||
plant   276 LLANETTPRILAATIKLISDNPKVMKELHREHEGIVRGKTEKETSITWEEYKSMTFTQMVINESL 340

  Fly   373 RLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDA-DVPQIHP 436
            |:....|.:.|.|..:.::....||||..| ||......:|:.::.|..|.|.|::. |:..|..
plant   341 RITSTAPTVFRIFDHEFQVGSYKIPAGWIF-MGYPNNHFNPKTYDDPLVFNPWRWEGKDLGAIVS 404

  Fly   437 YAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM--------NIVLRSANG 492
            ..||||.||.|.|:|.:||.|:|...:..|.|          .|.||        |.||...||
plant   405 RTYIPFGAGSRQCVGAEFAKLQMAIFIHHLSR----------DRWSMKIGTTILRNFVLMFPNG 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	115/489 (24%)
CYP702A1	NP_176744.1	p450	8..440	CDD:386267	112/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920