DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP96A8

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_175193.1	Gene:	CYP96A8 / 841171	AraportID:	AT1G47620	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	121/523 - (23%)
Similarity:	222/523 - (42%)	Gaps:	86/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FATLL----LWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDF---VKKNQRKYGRLYR 70
            |:.||    |..:.|.....|:|||..             |..::|.|.   |.:|.....:...
plant    28 FSYLLIKKTLQSYPWNWPVLGMLPGVL-------------LRLQRIYDCSVEVLENSNMTFQFKG 79

  Fly    71 VWILHQLAVFSTDPRDIEFVLSSQ-QHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFH 134
            .|.:....:.:.||.:|..::||. .:..|..::..:....|||::.:....|...|......|:
plant    80 PWFVGMDVLATVDPANIHHIMSSNFSNYIKGPIFHEIFEAFGDGIINTDAELWRDWRNASQLIFN 144

  Fly   135 FKILEQFVEIFDQQSAVMVEQLQSRADGMTP-----------INIFPVICLTALDI--IAETAMG 186
            .:..:.|       ||...:...:  ||:.|           :::..|......||  |..|...
plant   145 HQRYQNF-------SASTTKTKVN--DGLVPLFNHFANEEIVVDLEDVFQRFMYDITFIFITGTD 200

  Fly   187 TKINAQKNPNLPYVQAVNDVTNILIKRFI---HAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTE 248
            .:..:.:.|.:.:.:|::||.:.::.|.|   ..|:...||...|:    |:..||........|
plant   201 PRSLSIEMPEVEFSKALDDVGDAIVHRHITPRFVWKLQKWIGIGTE----KKMLKAHATFDRVCE 261

  Fly   249 NIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGA--PLSDEDIREEVDTFMFE 311
            .||..:||.|  .|:..|    .|..|::..:....:.|.:|....  |..|:.:|:....||..
plant   262 KIIAAKREEL--GSQGIT----YNSNGEREDLLTSFIKLDATKYEVLKPSHDKFLRDFTIGFMAA 320

  Fly   312 GHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRD------LGELKFMENVIKE 370
            |.|:|.|.:::..:.:|::|.|..::.|||...|      |.|..|      |.:|.::...:.|
plant   321 GRDSTASTLTWFFWNLSKNPNVLTKILQEINTNL------PRTGSDQDMSSYLNKLVYLHGALSE 379

  Fly   371 SLRLHPPVPMIGRW-FAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDADVPQ 433
            |:||:||:|...:. ..|||...|..:.:..|..:.|:.:.|....: |...||:|||:.::...
plant   380 SMRLYPPIPFQRKSPIKEDVLPSGHKVKSNINIMIFIYAMGRMKTIWGEDAMEFKPERWISETGG 444

  Fly   434 IH---PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL-----LPLGPEP------RHSMN 484
            :.   .|.::.|:||||.|:|:..||..||:.:.::|:::|:     ..:.|:|      :|.:.
plant   445 VRHEPSYKFLSFNAGPRTCLGKNLAMNLMKTVIVEILQNYEIKIVSGQKIEPKPGLILHMKHGLK 509

  Fly   485 IVL 487
            :.:
plant   510 VTM 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	114/500 (23%)
CYP96A8	NP_175193.1	p450	1..515	CDD:386267	121/523 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010