DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP87A2

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001184974.1	Gene:	CYP87A2 / 837830	AraportID:	AT1G12740	Length:	478	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	117/536 - (21%)
Similarity:	215/536 - (40%)	Gaps:	114/536 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVAFATLLL-----WDFLWRR---RGNGILPGPRPLPFLGNLLMYRGLDPEQIMD---FVKKNQR 63
            |:.:.:|||     |.:.||.   ||. :.||....|.||..:.:  ..|.:..|   |:|:..:
plant     4 LLIWVSLLLISITHWVYSWRNPKCRGK-LPPGSMGFPLLGESIQF--FKPNKTSDIPPFIKERVK 65

  Fly    64 ------KYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRK- 121
                  :||.:::..::.:..:.||| .|:.:.:.:|:.       :....|..|......|:|
plant    66 NDVDMCRYGPIFKTNLVGRPVIVSTD-ADLSYFVFNQEG-------RCFQSWYPDTFTHIFGKKN 122

  Fly   122 ---WHG------RRKIITPTFH---FKILEQF-------VEIFDQQSAVMVEQLQSRADGMTPIN 167
               .||      :..::|...|   .|:|.|.       :|::..|.:|   :|:.....|
plant   123 VGSLHGFMYKYLKNMVLTLFGHDGLKKMLPQVEMTANKRLELWSNQDSV---ELKDATASM---- 180

  Fly   168 IFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTE 232
               :..|||..:|:.....:..|.:.|    :|..:..:.:                |....|..
plant   181 ---IFDLTAKKLISHDPDKSSENLRAN----FVAFIQGLIS----------------FPFDIPGT 222

  Fly   233 A-----KRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID 292
            |     :.:.||:|::    .|:::||||....|     |.:..::           |:.:...:
plant   223 AYHKCLQGRAKAMKML----RNMLQERRENPRKN-----PSDFFDY-----------VIEEIQKE 267

  Fly   293 GAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVL--GEDRKSPVTL 355
            |..|::|...:.:...:|...:||:.|::..:..:|..|||.:||.:|...:|  .||..|.:|.
plant   268 GTILTEEIALDLMFVLLFASFETTSLALTLAIKFLSDDPEVLKRLTEEHETILRNREDADSGLTW 332

  Fly   356 RDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPD 420
            .:...:.:....|.|:.||...||.|.|....|::.:...||||....:....:..:||.::.|.
plant   333 EEYKSMTYTFQFINETARLANIVPAIFRKALRDIKFKDYTIPAGWAVMVCPPAVHLNPEMYKDPL 397

  Fly   421 EFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNI 485
            .|.|.|::..........::.|..|.|.|:|..|..|:|.:.:..|:..:..     |.....||
plant   398 VFNPSRWEGSKVTNASKHFMAFGGGMRFCVGTDFTKLQMAAFLHSLVTKYRW-----EEIKGGNI 457

  Fly   486 V----LRSANGVHLGL 497
            .    |:..||.|:.|
plant   458 TRTPGLQFPNGYHVKL 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	106/502 (21%)
CYP87A2	NP_001184974.1	p450	4..475	CDD:299894	117/536 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920