DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP86A1

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_200694.1	Gene:	CYP86A1 / 836003	AraportID:	AT5G58860	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	123/534 - (23%)
Similarity:	235/534 - (44%)	Gaps:	81/534 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWIL 74
            :.|.:...||.:...||    |.||:.|||:|: |.|...:..:|.|::..|.|..|..|:...:
plant    13 VAALSVYALWFYFLSRR----LTGPKVLPFVGS-LPYLIANRSRIHDWIADNLRATGGTYQTCTM 72

  Fly    75 --------HQLAVFSTDPRDIEFVLSSQ-QHITKNNLYK-LLNCWLGDGLLMSTGRKWHGRRKII 129
                    ......:..|:::|.:|.:: .:..|..::: ..:..||.|:..|.|..|..:||..
plant    73 VIPFVAKAQGFYTVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLMQRKTA 137

  Fly   130 TPTFHFKILEQFV------EIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTK 188
            ...|..:.|.|.:      .|.::...::...:|:.    .|:::..:......|.|.....|
plant   138 ALEFTTRTLRQAMARWVNGTIKNRLWLILDRAVQNN----KPVDLQDLFLRLTFDNICGLTFG-- 196

  Fly   189 INAQKNPNL--------PYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHD 245
                |:|..        |:..|.:..|...:||.::    ..:::|:.:......:||..|.:
plant   197 ----KDPETLSLDLPDNPFSVAFDTATEATLKRLLY----TGFLWRIQKAMGIGSEDKLKKSL-- 251

  Fly   246 FTENIIRERRETLVN---NSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDT 307
                   |..||.:|   ::::.:|.:::          |...|.:..::|..|..:.::.....
plant   252 -------EVVETYMNDAIDARKNSPSDDL----------LSRFLKKRDVNGNVLPTDVLQRIALN 299

  Fly   308 FMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDR--------KSPVTLRDLGELKFM 364
            |:..|.||::.|:|:..:.:..:.||:.::..|:..||.|.|        :.|:...:...|.::
plant   300 FVLAGRDTSSVALSWFFWLVMNNREVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVYL 364

  Fly   365 ENVIKESLRLHPPVPMIGRWFA-EDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERF 427
            :..:.|:|||:|.||...::.. :||...|..:|.|:..|..|:.:.|....: |...||||||:
plant   365 KAALAETLRLYPSVPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERW 429

  Fly   428 -DADVPQIHP----YAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPL-GPEPRHSMNIV 486
             .||..:...    |.::.|:||||.|:|:..|..:|||..|.:|..:.:.|: |......|::.
plant   430 LTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLT 494

  Fly   487 LRSANGVHLGLKPR 500
            |...||:.:.|:||
plant   495 LFMKNGLRVYLQPR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	114/505 (23%)
CYP86A1	NP_200694.1	CYP86A	70..501	CDD:410687	99/463 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920